Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18250301 | 0.91 | LMNA (0.49) | SMN1; SMN2LMNANPSR1TSHRMEN1 | |
| SCHEMBL26290413 | 0.84 | KDM4E (0.57) | SMN1; SMN2LMNANPSR1TSHRMEN1 | |
| SCHEMBL18250330 | 0.84 | KDM4E (0.57) | SMN1; SMN2LMNANPSR1TSHRMEN1 | |
| SCHEMBL18250756 | 0.84 | TSHR (0.49) | SMN1; SMN2LMNATSHRHTTKDM4E | |
| SCHEMBL18250302 | 0.79 | LMNA (0.47) | SMN1; SMN2LMNANPSR1TSHRMEN1 | |
| SCHEMBL17904688 | 0.78 | LMNA (0.51) | SMN1; SMN2LMNANPSR1TSHRMEN1 | |
| SCHEMBL14048505 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRHTTKDM4EALDH1A1 | |
| SCHEMBL10098954 | 0.77 | LMNA (0.66) | SMN1; SMN2LMNATSHRMEN1KMT2A | |
| SCHEMBL20206668 | 0.75 | ALDH1A1 (0.53) | SMN1; SMN2LMNAUSP2NPSR1MEN1 | |
| SCHEMBL18250699 | 0.74 | TSHR (0.51) | SMN1; SMN2LMNATSHRKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499529-B2 | Therapeutic uses of curcumin analogs for treatment of prostate cancer | CALIFORNIA STATE UNIVERSITY, FRESNO (US) | 2016-11-22 | — | — | US | disclosed |