SCHEMBL18253255

SCHEMBL18253255

c1ccc(N(c2ccccc2)c2ccc(-c3ccc(-c4cnc5c6ccccc6c6ccccc6c5n4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.37
ADK P55263 1/20 0.36
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPC1 O15118 5/20 0.34
RAB9A P51151 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
BCHE P06276 1/20 0.34
NOS1 P29475 2/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PDGFRB P09619 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12722971 0.98 CYP11B1 (0.38) CYP11B1ADKMAPTKDM4EALDH1A1
SCHEMBL18663514 0.90 ASIC3 (0.37) CYP11B1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL18253262 0.90 SMN1; SMN2 (0.35) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL18253258 0.90 ASIC3 (0.37) CYP11B1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL14983256 0.88 KDM4E (0.39) CYP11B1ADKKDM4EL3MBTL1KDR
SCHEMBL14983289 0.88 KDM4E (0.39) CYP11B1ADKKDM4EL3MBTL1KDR
SCHEMBL16543290 0.87 NPC1 (0.42) MAPTKDM4EALDH1A1L3MBTL1NPC1
SCHEMBL3288438 0.86 SGK1 (0.35) CYP11B1ADKNPC1RAB9ASMN1; SMN2
SCHEMBL14983251 0.86 KDM4E (0.40) CYP11B1ADKMAPTKDM4EL3MBTL1
SCHEMBL18241799 0.85 NPC1 (0.36) MAPTKDM4EALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029114-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-02 US disclosed
US-12029114-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-02 US disclosed
US-20210104677-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-04-08 US disclosed
US-10868256-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-12-15 US disclosed
US-20160343954-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-24 US disclosed
US-20160343954-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-24 US disclosed