SCHEMBL18253258

SCHEMBL18253258

c1ccc(N(c2ccccc2)c2ccc(-c3cccc(-c4cnc5c6ccccc6c6ccccc6c5n4)c3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ASIC3 Q9UHC3 1/20 0.37
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
KMO O15229 1/20 0.33
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 1/20 0.33
PDGFRB P09619 1/20 0.33
KDR P35968 1/20 0.33
FLT3 P36888 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
WNT3A P56704 1/20 0.32
PIK3CG P48736 2/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18663514 1.00 ASIC3 (0.37) ASIC3KDM4ENPC1RAB9AKMO
SCHEMBL18253260 0.93 ASIC3 (0.35) ASIC3KDM4ENPC1RAB9APDGFRB
SCHEMBL18253262 0.92 SMN1; SMN2 (0.35) KDM4ENPC1RAB9APDGFRBKDR
SCHEMBL18241799 0.91 NPC1 (0.36) KDM4ENPC1RAB9APDGFRBKDR
SCHEMBL18253255 0.90 CYP11B1 (0.37) KDM4ENPC1RAB9ACYP11B1PDGFRB
SCHEMBL12722971 0.89 CYP11B1 (0.38) KDM4ENPC1RAB9ACYP11B1PDGFRB
SCHEMBL31482975 0.89 ASIC3 (0.43) ASIC3KDM4ENPC1RAB9AKMO
SCHEMBL17222496 0.89 ASIC3 (0.43) ASIC3KDM4ENPC1RAB9AKMO
SCHEMBL16543245 0.87 ASIC3 (0.42) ASIC3KDM4ENPC1RAB9AKMO
SCHEMBL18663521 0.86 KDM4E (0.35) ASIC3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029114-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-02 US disclosed
US-12029114-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-02 US disclosed
US-20210104677-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-04-08 US disclosed
US-10868256-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-12-15 US disclosed
US-20160343954-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-24 US disclosed
US-20160343954-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-24 US disclosed