Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571374 | 0.69 | HDAC8 (0.50) | HDAC8DYRK1ADYRK2DYRK1B | |
| SCHEMBL17701192 | 0.67 | HDAC8 (0.34) | HDAC8DYRK1ADYRK2DYRK1B | |
| SCHEMBL11036129 | 0.67 | HDAC8 (0.31) | HDAC8DYRK1A | |
| SCHEMBL17701239 | 0.65 | CD38 (0.32) | HDAC8 | |
| SCHEMBL17701238 | 0.65 | DYRK1A (0.33) | HDAC8DYRK1ADYRK2DYRK1B | |
| SCHEMBL9454292 | 0.64 | DYRK1A (0.34) | HDAC8DYRK1ADYRK2DYRK1B | |
| SCHEMBL26635424 | 0.63 | HDAC8 (0.44) | HDAC8DYRK1ADYRK2DYRK1B | |
| SCHEMBL12945553 | 0.63 | CD38 (0.35) | HDAC8DYRK1ADYRK2DYRK1B | |
| SCHEMBL9077755 | 0.61 | HDAC8 (0.33) | HDAC8DYRK1ADYRK2DYRK1B | |
| SCHEMBL7221447 | 0.61 | NPC1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493844-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | Bayer CropScience AG (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011054436-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-12 | — | — | WO | disclosed |