SCHEMBL17701239

SCHEMBL17701239

[c]1ncnc(-c2cncs2)n1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CD38 P28907 2/20 0.32
HDAC8 Q9BY41 1/20 0.30
LATS1 O95835 1/20 0.30
CHEK1 O14757 1/20 0.30
CHEK2 O96017 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11240898 0.72
SCHEMBL17701238 0.70 DYRK1A (0.33) CD38HDAC8LATS1CHEK1CHEK2
SCHEMBL17701192 0.68 HDAC8 (0.34) HDAC8LATS1CHEK1CHEK2
SCHEMBL3694038 0.67 DYRK1A (0.42) CD38HDAC8LATS1CHEK1CHEK2
SCHEMBL571374 0.67 HDAC8 (0.50) CD38HDAC8CHEK1CHEK2
SCHEMBL17701186 0.67 PIM1 (0.33) CD38HDAC8
SCHEMBL17701232 0.67 DYRK1A (0.36) HDAC8
SCHEMBL17701204 0.66 DYRK1A (0.41) CD38HDAC8CHEK1CHEK2
SCHEMBL1825565 0.65 HDAC8 (0.32) HDAC8
SCHEMBL26635424 0.64 HDAC8 (0.44) HDAC8LATS1CHEK1CHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160118598-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME JNC CORPORATION (JP) 2016-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160118598-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME HVCN1, VDAC1, SLC26A3 CD38 2387/4885HDAC8 3178/4885LATS1 1953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.