Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571374 | 0.69 | HDAC8 (0.50) | DYRK1ADYRK2DYRK1BHDAC8PIM1 | |
| SCHEMBL1360297 | 0.69 | ALDH1A1 (0.46) | — | |
| SCHEMBL678452 | 0.68 | KDM4E (0.50) | — | |
| SCHEMBL17701244 | 0.68 | HDAC8 (0.32) | DYRK1ADYRK2DYRK1BHDAC8PIM1 | |
| SCHEMBL5783399 | 0.68 | ALDH1A1 (0.35) | — | |
| SCHEMBL7240451 | 0.67 | ATM (0.33) | — | |
| SCHEMBL3610416 | 0.67 | HDAC8 (0.39) | DYRK1ADYRK2DYRK1BHDAC8PIM1 | |
| SCHEMBL9263876 | 0.67 | IMPDH2 (0.36) | DYRK1ADYRK2DYRK1BHDAC8PIM1 | |
| SCHEMBL18437163 | 0.67 | HDAC8 (0.31) | DYRK1AHDAC8PIM1IMPDH2 | |
| SCHEMBL17625930 | 0.65 | ATM (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0318860-B1 | SUBSTITUTED ALKYLAMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0318860-A2 | Substituted alkylamine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |