Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.67 |
| ▸ | CTSL | P07711 | 5/20 | 0.63 |
| ▸ | CTSS | P25774 | 4/20 | 0.63 |
| ▸ | CTSB | P07858 | 3/20 | 0.63 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8276390 | 1.00 | CTSK (0.67) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL13519748 | 0.88 | CTSK (0.72) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL1709151 | 0.87 | ALDH1A1 (0.64) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL1701751 | 0.87 | ALDH1A1 (0.64) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL14611591 | 0.87 | CTSK (0.74) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27493720 | 0.86 | CTSK (0.69) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL27493719 | 0.86 | CTSK (0.69) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL30065522 | 0.86 | CTSK (0.69) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL7953394 | 0.85 | CTSK (0.72) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL1823902 | 0.85 | CTSK (0.76) | CTSKCTSLCTSSCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016185450-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2016-11-24 | — | — | WO | disclosed |