Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.66 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.62 |
| ▸ | CTSK | P43235 | 8/20 | 0.61 |
| ▸ | CTSL | P07711 | 4/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827177 | 1.00 | REN (0.66) | RENCAPN1CTSKCTSLCTSS | |
| SCHEMBL20825305 | 1.00 | REN (0.66) | RENCAPN1CTSKCTSLCTSS | |
| SCHEMBL18257558 | 1.00 | REN (0.66) | RENCAPN1CTSKCTSLCTSS | |
| SCHEMBL85181 | 1.00 | REN (0.66) | RENCAPN1CTSKCTSLCTSS | |
| SCHEMBL18257506 | 1.00 | REN (0.66) | RENCAPN1CTSKCTSLCTSS | |
| SCHEMBL23616209 | 1.00 | REN (0.66) | RENCAPN1CTSKCTSLCTSS | |
| SCHEMBL9551248 | 0.97 | REN (0.68) | RENCAPN1CTSKCTSLCTSS | |
| SCHEMBL15255353 | 0.96 | REN (0.66) | RENCAPN1CTSKCTSLCTSS | |
| SCHEMBL9551300 | 0.96 | REN (0.66) | RENCAPN1CTSKCTSLCTSS | |
| SCHEMBL4576421 | 0.94 | CTSK (0.65) | RENCAPN1CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016185450-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2016-11-24 | — | — | WO | disclosed |