Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18250963 | 0.84 | CTSK (0.35) | CTSKTDP1CA1CA2CA7 | |
| SCHEMBL21738917 | 0.78 | CTSK (0.35) | APLNRCTSKTDP1CA1CA2 | |
| SCHEMBL17268906 | 0.78 | CTSK (0.35) | APLNRCTSKTDP1CA1CA2 | |
| SCHEMBL20134162 | 0.77 | CTSK (0.42) | CTSK | |
| SCHEMBL18857615 | 0.75 | TDP1 (0.38) | CTSKTDP1CA1CA2TSHR | |
| SCHEMBL25605409 | 0.75 | APLNR (0.44) | APLNRCTSKTDP1CA1CA2 | |
| SCHEMBL17273226 | 0.74 | TDP1 (0.34) | CTSKTDP1CA1CA2CA7 | |
| SCHEMBL20933070 | 0.73 | TDP1 (0.42) | CTSKTDP1CA1CA2CA7 | |
| SCHEMBL23743602 | 0.73 | CTSK (0.43) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL21071470 | 0.73 | MEN1 (0.38) | APLNRCTSKTDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016185425-A1 | DENDRI-TAC AND THEIR USE AS THERANOSTICS | UNIVERSITE D'AVIGNON ET DES PAYS DU VAUCLUSE (FR) | 2016-11-24 | — | — | WO | disclosed |