SCHEMBL18258300

SCHEMBL18258300

CC/N=c1\cc2oc3cc(NCC)c(C)cc3c(-c3ccccc3C(=O)N(C)CCCC(=O)O)c-2cc1C

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ USP2 O75604 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ CASP1 P29466 1/20 0.34
▸ BRCA1 P38398 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ CASP7 P55210 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ FTO Q9C0B1 2/20 0.32
▸ HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22247631 0.92 FTO (0.33) KDM4EMEN1USP2CYP3A4MAPT
SCHEMBL22219891 0.92 HDAC6 (0.32) HDAC6
SCHEMBL14078004 0.92 KDM4E (0.31) KDM4EMEN1USP2CYP3A4MAPT
SCHEMBL14078007 0.91 MEN1 (0.32) KDM4EMEN1USP2CYP3A4MAPT
SCHEMBL1095524 0.90 HDAC6 (0.33) USP2HDAC6
SCHEMBL22247630 0.89 — —
SCHEMBL25208865 0.87 KDM4E (0.34) KDM4EMEN1USP2CYP3A4MAPT
SCHEMBL26428065 0.87 KDM4E (0.34) KDM4EMEN1USP2CYP3A4MAPT
SCHEMBL1095520 0.86 FTO (0.43) KDM4EMEN1USP2CYP3A4MAPT
SCHEMBL3626595 0.86 FTO (0.43) KDM4EMEN1USP2CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230272470-A1 ULTRABRIGHT DNA NANOSTRUCTURES FOR BIOSENSING QUANTUM SI INC (US) 2023-08-31 — — US disclosed
US-20230272470-A1 ULTRABRIGHT DNA NANOSTRUCTURES FOR BIOSENSING QUANTUM SI INC (US) 2023-08-31 — — US disclosed
US-11001875-B2 Methods for nucleic acid sequencing Quantum-Si Incorporated (US) 2021-05-11 — — US disclosed
US-20190330688-A1 METHODS FOR NUCLEIC ACID SEQUENCING Quantum-Si Incorporated (US) 2019-10-31 — — US disclosed
US-10174363-B2 Methods for nucleic acid sequencing Quantum-Si Incorporated (US) 2019-01-08 — — US disclosed
US-20170107562-A1 METHODS FOR NUCLEIC ACID SEQUENCING Quantum-Si Incorporated (US) 2017-04-20 — — US disclosed
US-20170107562-A1 METHODS FOR NUCLEIC ACID SEQUENCING Quantum-Si Incorporated (US) 2017-04-20 — — US disclosed
WO-2016187580-A1 METHOD OF DETERMINING THE SEQUENCE OF A NUCLEAR ACID USING TIME RESOLVED LUMINESCENCE Quantum-Si Incorporated (US) 2016-11-24 — — WO disclosed
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