SCHEMBL1095520

SCHEMBL1095520

CC/N=c1\cc2oc3cc(NCC)c(C)cc3c(-c3ccccc3C(=O)O)c-2cc1C

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 2/20 0.43
▸ KDM4E B2RXH2 5/20 0.41
▸ POLB P06746 3/20 0.41
▸ MAPT P10636 4/20 0.41
▸ USP2 O75604 4/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ BLM P54132 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ HPGD P15428 3/20 0.41
▸ THRB P10828 2/20 0.41
▸ RECQL P46063 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ CASP1 P29466 2/20 0.41
▸ CASP7 P55210 2/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ BRCA1 P38398 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ MYC P01106 1/20 0.36
▸ ABCB1 P08183 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3626595 1.00 FTO (0.43) FTOKDM4EPOLBMAPTUSP2
SCHEMBL9915064 1.00 FTO (0.43) FTOKDM4EPOLBMAPTUSP2
Hydrochloric Acid SCHEMBL9638604 0.99 FTO (0.42) FTOKDM4EPOLBMAPTUSP2
Hydrochloric Acid SCHEMBL12492233 0.99 FTO (0.42) FTOKDM4EPOLBMAPTUSP2
SCHEMBL9637519 0.97 FTO (0.43) FTOKDM4EPOLBMAPTUSP2
Perchlorate SCHEMBL5605513 0.96 FTO (0.40) FTOKDM4EPOLBMAPTUSP2
Perchlorate SCHEMBL29579793 0.96 FTO (0.40) FTOKDM4EPOLBMAPTUSP2
Perchlorate SCHEMBL5605515 0.96 FTO (0.40) FTOKDM4EPOLBMAPTUSP2
Rhodamine 6G SCHEMBL7454756 0.93 FTO (0.39) FTOKDM4EPOLBMAPTUSP2
SCHEMBL13428306 0.93 FTO (0.35) FTOKDM4EPOLBMAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160377605-A1 LYSOSOMAL ATP SELECTIVE TWO-PHOTON ABSORBING FLUORESCENT PROBE POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2016-12-29 — — US claimed
US-12011433-B2 Mofezolac derivatives as multi-functions selective COX-1 inhibitors ITEL TELECOMUNICAZIONI S.R.L. (IT) 2024-06-18 — — US disclosed
EP-3391056-B1 CHROMOGENIC PEROXIDASE SUBSTRATES AGILENT TECHNOLOGIES INC (US) 2024-01-17 — — EP disclosed
US-20230002816-A1 CHROMOGENIC PEROXIDASE SUBSTRATES DAKO DENMARK APS (DK) 2023-01-05 — — US disclosed
US-11466314-B2 Chromogenic peroxidase substrates AGILENT TECHNOLOGIES, INC. (US) 2022-10-11 — — US disclosed
EP-3782990-A1 MOFEZOLAC DERIVATIVES AS MULTI-FUNCTIONS SELECTIVE COX-1 INHIBITORS Università degli Studi di Bari "Aldo Moro" (IT) 2021-02-24 — — EP disclosed
EP-3782990-A1 MOFEZOLAC DERIVATIVES AS MULTI-FUNCTIONS SELECTIVE COX-1 INHIBITORS Università degli Studi di Bari "Aldo Moro" (IT) 2021-02-24 — — EP disclosed
US-20210023055-A1 MOFEZOLAC DERIVATIVES AS MULTI-FUNCTIONS SELECTIVE COX-1 INHIBITORS ITEL TELECOMUNICAZIONI S.R.L. (IT) 2021-01-28 — — US disclosed
US-20200157613-A1 CHROMOGENIC PEROXIDASE SUBSTRATES DAKO DENMARK APS (DK) 2020-05-21 — — US disclosed
US-10450462-B2 Colored composition FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 — — US disclosed
US-20100059740-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2010-03-11 — — US disclosed
US-20090219526-A1 REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-03 — — US disclosed
WO-2008087031-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2008-07-24 — — WO disclosed
US-20080159351-A1 MECHANICALLY TUNABLE ELASTOMERIC OPTOFLUIDIC DISTRIBUTED FEEDBACK DYE LASERS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2008-07-03 — — US disclosed
EP-1107057-A1 Photographic colour filter array film EASTMAN KODAK COMPANY (US) 2001-06-13 — — EP disclosed
EP-0610994-B1 Photographic elements for producing blue, green and red exposure records of the same hue and methods for the retrieval and differentiation of the exposure records KODAK LTD (GB) 1997-12-10 — — EP disclosed
US-5420003-A SIMPLIFIED FILM AND PROCESSING FOR COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1995-05-30 — — US disclosed
US-5350650-A Color separations, scanning developed image with colored light beams modulated by dye images, computer recording and processsing of data EASTMAN KODAK COMPANY (US) 1994-09-27 — — US disclosed
WO-1990015441-A1 LASER DYE LIQUIDS, LASER DYE INSTRUMENTS AND METHODS EXCITON INCORPORATED (US) 1990-12-13 — — WO disclosed
US-4896329-A Laser dye liquids, laser dye instruments and methods EXCITON INCORPORATED (US) 1990-01-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10450462-B2 Colored composition IK, HEATR6, CYBA FTO 1211/4885KDM4E 3453/4885POLB 2130/4885
US-11466314-B2 Chromogenic peroxidase substrates MPO, TPO, TYR FTO 2730/4885KDM4E 4703/4885POLB 1946/4885
US-20200157613-A1 CHROMOGENIC PEROXIDASE SUBSTRATES MPO, TPO, TYR FTO 2730/4885KDM4E 4703/4885POLB 1946/4885
US-20230002816-A1 CHROMOGENIC PEROXIDASE SUBSTRATES MPO, TPO, TYR FTO 2730/4885KDM4E 4703/4885POLB 1946/4885
US-20160377605-A1 LYSOSOMAL ATP SELECTIVE TWO-PHOTON ABSORBING FLUORESCENT PROBE LAMP2, GAA, LAMP1 FTO 4221/4885KDM4E 4544/4885POLB 2601/4885
US-20210023055-A1 MOFEZOLAC DERIVATIVES AS MULTI-FUNCTIONS SELECTIVE COX-1 INHIBITORS PTGS1, HMOX1, HMGB1 FTO 2210/4885KDM4E 980/4885POLB 3007/4885
US-20090219526-A1 REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY SRMS, UQCRB, UQCRC1 FTO 3044/4885KDM4E 3862/4885POLB 748/4885
US-12011433-B2 Mofezolac derivatives as multi-functions selective COX-1 inhibitors PTGS1, HMOX1, HMGB1 FTO 2210/4885KDM4E 980/4885POLB 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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