Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817892 | 1.00 | ITGB1 (0.45) | ITGB1ITGA4POLBATM | |
| SCHEMBL7382803 | 1.00 | ITGB1 (0.45) | ITGB1ITGA4POLBATM | |
| Tromethamine SCHEMBL1820966 | 0.95 | ITGB1 (0.41) | ITGB1ITGA4POLB | |
| SCHEMBL7417699 | 0.94 | ITGB1 (0.49) | ITGB1ITGA4 | |
| SCHEMBL7101082 | 0.94 | ITGB1 (0.49) | ITGB1ITGA4 | |
| SCHEMBL7102059 | 0.94 | ITGB1 (0.49) | ITGB1ITGA4 | |
| SCHEMBL7099781 | 0.93 | ITGB1 (0.49) | ITGB1ITGA4 | |
| Tromethamine SCHEMBL1822020 | 0.90 | ITGB1 (0.46) | ITGB1ITGA4 | |
| SCHEMBL1825542 | 0.89 | ITGB1 (0.42) | ITGB1ITGA4POLBATM | |
| SCHEMBL7384383 | 0.89 | ITGB1 (0.42) | ITGB1ITGA4POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4686029-B2 | — | — | 2011-05-18 | — | — | JP | claimed |
| EP-1183241-B1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | AVENTIS PHARMA GMBH (DE) | 2003-09-17 | — | — | EP | claimed |
| JP-2002544261-A | — | — | 2002-12-24 | — | — | JP | claimed |
| US-6399643-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-04 | — | — | US | claimed |
| EP-1183241-A1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | Aventis Pharma Deutschland GmbH (DE) | 2002-03-06 | — | — | EP | claimed |
| WO-2000069831-A1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-23 | — | — | WO | claimed |