Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417699 | 1.00 | ITGB1 (0.49) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7101082 | 1.00 | ITGB1 (0.49) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7099781 | 0.99 | ITGB1 (0.49) | ITGB1ITGA4ITGB7 | |
| Tromethamine SCHEMBL1822020 | 0.95 | ITGB1 (0.46) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7384383 | 0.95 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL1825542 | 0.95 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL1817374 | 0.95 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7099782 | 0.94 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL1817892 | 0.94 | ITGB1 (0.45) | ITGB1ITGA4 | |
| SCHEMBL1825903 | 0.94 | ITGB1 (0.45) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183241-B1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | AVENTIS PHARMA GMBH (DE) | 2003-09-17 | — | — | EP | claimed |
| US-6399643-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-04 | — | — | US | claimed |