Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30034855 | 0.91 | DNMT1 (0.48) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL191449 | 0.91 | DNMT1 (0.48) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Ammonia Solution, Strong SCHEMBL12818906 | 0.89 | DNMT1 (0.47) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Phosphine SCHEMBL28227864 | 0.89 | DNMT1 (0.47) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Methane SCHEMBL28083172 | 0.89 | DNMT1 (0.47) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Hydrogen Sulfide SCHEMBL28212457 | 0.89 | DNMT1 (0.47) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL31690700 | 0.87 | DNMT1 (0.40) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL29321981 | 0.86 | DNMT1 (0.44) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL17442108 | 0.85 | ALDH1A1 (0.50) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL31603915 | 0.85 | ALDH1A1 (0.50) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708351-B2 | Alkenes as alkyne equivalents in radical cascades terminated by fragmentations | The Florida State University Research Foundation, Inc. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160347778-A1 | ALKENES AS ALKYNE EQUIVALENTS IN RADICAL CASCADES TERMINATED BY FRAGMENTATIONS | The Florida State University Research Foundation, Inc. | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347778-A1 | ALKENES AS ALKYNE EQUIVALENTS IN RADICAL CASCADES TERMINATED BY FRAGMENTATIONS | AOC3, OR51E2, AOC2 | DNMT1 920/4885ALDH1A1 913/4885HSD17B10 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.