Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80432 | 0.97 | CYP3A4 (0.67) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR | |
| SCHEMBL288653 | 0.95 | CYP3A4 (0.64) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR | |
| Calcium SCHEMBL10786160 | 0.95 | CYP3A4 (0.64) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR | |
| SCHEMBL1230777 | 0.95 | CYP3A4 (0.64) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR | |
| SCHEMBL18835723 | 0.95 | CYP3A4 (0.64) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR | |
| SCHEMBL23087841 | 0.95 | CYP3A4 (0.64) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR | |
| Magnesium SCHEMBL10786879 | 0.95 | CYP3A4 (0.64) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR | |
| Barium SCHEMBL10790747 | 0.95 | CYP3A4 (0.64) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR | |
| SCHEMBL8281040 | 0.95 | CYP3A4 (0.64) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR | |
| SCHEMBL10842882 | 0.95 | CYP3A4 (0.64) | CYP3A4ALDH1A1L3MBTL1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303350-B1 | BASE-CATALYZED SILYLATION OF TERMINAL OLEFINIC C-H BONDS | CALIFORNIA INST OF TECHN (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-3909959-A1 | BASE-CATALYZED SILYLATION OF TERMINAL OLEFINIC C-H BONDS | California Institute of Technology (US) | 2021-11-17 | — | — | EP | disclosed |
| US-10059726-B2 | Base-catalyzed silylation of terminal olefinic C—H bonds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-08-28 | — | — | US | disclosed |
| EP-3303350-A1 | BASE-CATALYZED SILYLATION OF TERMINAL OLEFINIC C-H BONDS | California Institute of Technology (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016196250-A1 | BASE-CATALYZED SILYLATION OF TERMINAL OLEFINIC C-H BONDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-12-08 | — | — | WO | disclosed |
| US-20160347776-A1 | BASE-CATALYZED SILYLATION OF TERMINAL OLEFINIC C-H BONDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347776-A1 | BASE-CATALYZED SILYLATION OF TERMINAL OLEFINIC C-H BONDS | DOHH, OSBP, HRH3 | CYP3A4 2252/4885ALDH1A1 2225/4885L3MBTL1 762/4885 |
| US-10059726-B2 | Base-catalyzed silylation of terminal olefinic C—H bonds | DOHH, OSBP, OSBP2 | CYP3A4 2228/4885ALDH1A1 2309/4885L3MBTL1 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.