SCHEMBL18263247

SCHEMBL18263247

CC1CC1(CCCCCCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
LMNA P02545 2/20 0.44
NFKB1 P19838 1/20 0.44
PMP22 Q01453 1/20 0.44
PPARG P37231 8/20 0.42
GPR84 Q9NQS5 8/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42
HDAC11 Q96DB2 5/20 0.42
PTPN1 P18031 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
FFAR1 O14842 2/20 0.42
FFAR4 Q5NUL3 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278015 1.00 TSHR (0.44) TSHRLMNANFKB1PMP22PPARG
SCHEMBL251265 1.00 TSHR (0.44) TSHRLMNANFKB1PMP22PPARG
SCHEMBL250482 0.98 LMNA (0.42) TSHRLMNANFKB1PMP22PPARG
SCHEMBL250313 0.92 LMNA (0.39) TSHRLMNANFKB1PMP22PPARG
SCHEMBL2049103 0.83 GPR84 (0.39) TSHRPPARGGPR84PPARDPPARA
SCHEMBL10937554 0.83 GPR84 (0.39) TSHRPPARGGPR84PPARDPPARA
SCHEMBL2053235 0.81 AKR1B1 (0.37) TSHRPPARGGPR84PPARDPPARA
Ethylene Glycol SCHEMBL4414824 0.79 CAMK2A (0.37) GPR84FFAR1FFAR4
Benzoic Acid SCHEMBL10816773 0.78 HDAC3 (0.41) TSHRLMNAPPARAHDAC11ALDH1A1
SCHEMBL10895051 0.75 TSHR (0.41) TSHRLMNANFKB1PMP22PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3298076-A1 POLYMER COMPOSITION SABIC Global Technologies B.V. (NL) 2018-03-28 EP claimed
EP-3298077-A1 POLYMER COMPOSITION SABIC Global Technologies B.V. (NL) 2018-03-28 EP claimed
EP-3298078-A1 IMPROVED HETEROPHASIC POLYPROPYLENE SABIC Global Technologies B.V. (NL) 2018-03-28 EP claimed
WO-2016198243-A1 IMPROVED HETEROPHASIC POLYPROPYLENE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-15 WO claimed
WO-2016188818-A1 POLYMER COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-01 WO claimed
WO-2016188817-A1 POLYMER COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-01 WO claimed
EP-4013809-A1 USE OF A COMPOSITION FOR THE MANUFACTURE OF A FOAMED ARTICLE SABIC Global Technologies, B.V. (NL) 2022-06-22 EP disclosed
WO-2021032378-A1 USE OF A COMPOSITION FOR THE MANUFACTURE OF A FOAMED ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-02-25 WO disclosed
EP-3298077-A1 POLYMER COMPOSITION SABIC Global Technologies B.V. (NL) 2018-03-28 EP disclosed
EP-3298076-A1 POLYMER COMPOSITION SABIC Global Technologies B.V. (NL) 2018-03-28 EP disclosed
EP-3298078-A1 IMPROVED HETEROPHASIC POLYPROPYLENE SABIC Global Technologies B.V. (NL) 2018-03-28 EP disclosed
WO-2016198243-A1 IMPROVED HETEROPHASIC POLYPROPYLENE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-15 WO disclosed
WO-2016188817-A1 POLYMER COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-01 WO disclosed
WO-2016188818-A1 POLYMER COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-01 WO disclosed