Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24588839 | 0.92 | GPR119 (0.43) | GPR119HPGDUSP2SMN1; SMN2EPHX2 | |
| SCHEMBL16054753 | 0.91 | GPR119 (0.49) | GPR119HPGDUSP2SMN1; SMN2EPHX2 | |
| SCHEMBL623537 | 0.89 | GPR119 (0.50) | GPR119HPGDUSP2SMN1; SMN2EPHX2 | |
| SCHEMBL30901515 | 0.87 | HPGD (0.39) | GPR119HPGDUSP2SMN1; SMN2EPHX2 | |
| SCHEMBL23228620 | 0.87 | HPGD (0.39) | GPR119HPGDUSP2SMN1; SMN2EPHX2 | |
| Hydrochloric Acid SCHEMBL29691280 | 0.85 | HPGD (0.38) | GPR119HPGDUSP2SMN1; SMN2EPHX2 | |
| SCHEMBL17107663 | 0.85 | CYP11B2 (0.47) | GPR119HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL9994757 | 0.84 | CYP11B2 (0.46) | GPR119USP2SMN1; SMN2EPHX2 | |
| SCHEMBL24753361 | 0.84 | HPGD (0.49) | GPR119HPGDUSP2SMN1; SMN2EPHX2 | |
| SCHEMBL20461030 | 0.84 | HPGD (0.49) | GPR119HPGDUSP2SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096858-A1 | COMPOUNDS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| EP-4351583-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2016190847-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2016-12-01 | — | — | WO | disclosed |