Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656389 | 0.71 | TSHR (0.39) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL11510699 | 0.70 | ALDH1A1 (0.36) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL10935007 | 0.70 | ALDH1A1 (0.40) | TSHRALDH1A1L3MBTL1LMNAKDM4E | |
| SCHEMBL2243707 | 0.70 | NPSR1 (0.44) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL18458675 | 0.69 | ALDH1A1 (0.42) | TSHRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL13159021 | 0.68 | ALDH1A1 (0.42) | TSHRALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL11050018 | 0.68 | KMT2A (0.38) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL7411647 | 0.67 | SIGMAR1 (0.49) | KMT2ATSHRALDH1A1L3MBTL1LMNA | |
| SCHEMBL13158953 | 0.67 | MEN1 (0.40) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL7409467 | 0.66 | SIGMAR1 (0.41) | ALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987393-B2 | Catalyst component for the polymerization of olefins having a guanidinate ligand | LANXESS ELASTOMERS B.V. (NL) | 2015-03-24 | — | — | US | disclosed |
| US-20130079478-A1 | CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND | LANXESS ELASTOMERS B.V. | 2013-03-28 | — | — | US | disclosed |
| EP-2496612-A1 | CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND | Lanxess Elastomers B.V. (NL) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011054927-A1 | CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND | DSM IP ASSETS B.V. (NL) | 2011-05-12 | — | — | WO | disclosed |
| EP-2319874-A1 | Catalyst component for the polymerization of olefins having a guanidinate ligand | DSM IP Assets B.V. (NL) | 2011-05-11 | — | — | EP | disclosed |