SCHEMBL1826535

SCHEMBL1826535

c1ccc2c(c1)ccc1c3c(ccc12)CCC3

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.54
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPT P10636 2/20 0.46
CYP2A6 P11509 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP1A2 P05177 1/20 0.46
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ACHE P22303 1/20 0.46
SLC6A2 P23975 1/20 0.46
AHR P35869 1/20 0.46
KIF11 P52732 1/20 0.45
PAX8 Q06710 1/20 0.41
HIF1A Q16665 1/20 0.40
CYP1B1 Q16678 1/20 0.40
NQO1 P15559 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29554780 1.00 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10MAPTCYP2A6
SCHEMBL29580834 1.00 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10MAPTCYP2A6
SCHEMBL28077721 0.96 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10MAPTCYP2A6
Chrysene SCHEMBL27616409 0.96 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10MAPTCYP2A6
SCHEMBL27740850 0.96 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10MAPTCYP2A6
Phenanthrene SCHEMBL27372954 0.96 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10MAPTCYP2A6
SCHEMBL2089665 0.96 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10MAPTCYP2A6
SCHEMBL30928215 0.96 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10MAPTCYP2A6
SCHEMBL21176632 0.96 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10MAPTCYP2A6
SCHEMBL30329691 0.94 HPRT1 (0.52) HPRT1ALDH1A1HSD17B10MAPTCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
US-20230045778-A9 HETEROGENEOUS HYDROGEN-CATALYST SOLID FUEL REACTION MIXTURE AND REACTOR BRILLIANT LIGHT POWER, INC. (US) 2023-02-09 US disclosed
US-20200299130-A1 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BRILLIANT LIGHT POWER, INC. (US) 2020-09-24 US disclosed
EP-2318307-A2 HETEROGENEOUS HYDROGEN-CATALYST REACTOR Blacklight Power, Inc. (US) 2011-05-11 EP disclosed
WO-2010014684-A2 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BLACKLIGHT POWER, INC. (US) 2010-02-04 WO disclosed
US-5480913-A DIHYDRO-PHENANTHRENE DERIVATIVES, SIDE EFFECT REDUCTION ARCH DEVELOPMENT CORPORATION (US) 1996-01-02 US disclosed
EP-0363128-B1 ANTI-ANDROGEN COMPOUNDS ARCH DEVELOPMENT CORPORATION (US) 1993-09-01 EP disclosed
US-5208263-A Dihydrophenanthrene derivatives ARCH DEVELOPMENT CORPORATION (US) 1993-05-04 US disclosed
US-5047304-A Azo Pigment as Charge Generating Substance CANON KABUSHIKI KAISHA (JP) 1991-09-10 US disclosed
EP-0363128-A2 Anti-androgen compounds ARCH DEVELOPMENT CORPORATION (US) 1990-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 HPRT1 3652/4885ALDH1A1 3874/4885HSD17B10 1170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.