Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028421 | 0.88 | MTNR1A (0.68) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL7028418 | 0.88 | MTNR1A (0.68) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL7028422 | 0.88 | MTNR1A (0.68) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL10424645 | 0.87 | MTNR1A (0.67) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL10424644 | 0.87 | MTNR1A (0.67) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL18265480 | 0.87 | MTNR1A (0.67) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL29216352 | 0.85 | MAPT (0.57) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL29216351 | 0.85 | MAPT (0.57) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL11582550 | 0.85 | MAPT (0.64) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL11582552 | 0.85 | MAPT (0.64) | MEN1NR1I2LMNAPGRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3097904-B1 | DEPIGMENTING AGENTS TO LIGHTEN THE SKIN | AFFICHEM (FR) | 2019-08-14 | — | — | EP | disclosed |
| WO-2016193220-A1 | SKIN PIGMENTATION MODIFIERS TO DARKEN OR LIGHTEN THE SKIN | AFFICHEM (FR) | 2016-12-08 | — | — | WO | disclosed |
| EP-3097904-A1 | DEPIGMENTING AGENTS TO LIGHTEN THE SKIN | Affichem (FR) | 2016-11-30 | — | — | EP | disclosed |