Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29216351 | 1.00 | MAPT (0.57) | MAPTMEN1NR1I2LMNAPGR | |
| SCHEMBL30105657 | 0.88 | PTGES (0.59) | MAPTMEN1NR1I2LMNAPGR | |
| SCHEMBL30105600 | 0.88 | PTGES (0.59) | MAPTMEN1NR1I2LMNAPGR | |
| SCHEMBL10424853 | 0.87 | PTGES (0.60) | MAPTMEN1NR1I2LMNAPGR | |
| SCHEMBL10424852 | 0.87 | PTGES (0.60) | MAPTMEN1NR1I2LMNAPGR | |
| SCHEMBL18292844 | 0.87 | MEN1 (0.56) | MAPTMEN1NR1I2LMNAPGR | |
| SCHEMBL9369362 | 0.85 | CA12 (0.58) | MAPTLMNAKMT2ACA12CA1 | |
| SCHEMBL18265490 | 0.85 | MEN1 (0.63) | MAPTMEN1NR1I2LMNAPGR | |
| SCHEMBL9369369 | 0.85 | CA12 (0.58) | MAPTLMNAKMT2ACA12CA1 | |
| SCHEMBL11582552 | 0.82 | MAPT (0.64) | MAPTMEN1NR1I2LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |