Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18265692 | 0.78 | SMN1; SMN2 (0.40) | PCSK9CA1CA2LMNAHDAC3 | |
| SCHEMBL18265694 | 0.78 | PCSK9 (0.39) | PCSK9CA1CA2HDAC8LPL | |
| SCHEMBL6663731 | 0.77 | PCSK9 (0.63) | PCSK9MAPK1SMN1; SMN2LPLLIPG | |
| SCHEMBL14085646 | 0.72 | PCSK9 (0.52) | PCSK9TSHRHDAC3HDAC1HDAC2 | |
| SCHEMBL5710442 | 0.71 | PCSK9 (0.55) | PCSK9CYP1A2CYP2D6CYP2C19MAPK1 | |
| SCHEMBL6128348 | 0.71 | PSMD14 (0.42) | CA1CA2HDAC3HDAC1HDAC2 | |
| SCHEMBL16667265 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2LPLLIPGMGLLTRPV1 | |
| SCHEMBL23367835 | 0.70 | PCSK9 (0.53) | PCSK9CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL6661937 | 0.70 | PCSK9 (0.53) | PCSK9CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL5802656 | 0.70 | PCSK9 (0.53) | PCSK9CYP1A2CYP2D6CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3098226-A1 | BORATE-BASED BASE GENERATOR, AND BASE-REACTIVE COMPOSITION COMPRISING SUCH BASE GENERATOR | Wako Pure Chemical Industries, Ltd. (JP) | 2016-11-30 | — | — | EP | disclosed |