Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 4/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14085646 | 0.85 | PCSK9 (0.52) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL16667265 | 0.80 | SMN1; SMN2 (0.42) | LPLLIPGTRPV1MGLLGAA | |
| SCHEMBL6661937 | 0.79 | PCSK9 (0.53) | LPLLIPG | |
| SCHEMBL5802656 | 0.79 | PCSK9 (0.53) | LPLLIPG | |
| SCHEMBL23367835 | 0.79 | PCSK9 (0.53) | LPLLIPG | |
| SCHEMBL18202358 | 0.78 | LIPG (0.45) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL5710442 | 0.77 | PCSK9 (0.55) | LPLLIPG | |
| Water SCHEMBL6656586 | 0.76 | PCSK9 (0.50) | LPLLIPG | |
| SCHEMBL18265693 | 0.71 | PCSK9 (0.39) | LPLLIPGTRPV1MGLLHDAC3 | |
| SCHEMBL18265694 | 0.71 | PCSK9 (0.39) | LPLLIPGTRPV1MGLLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450893-A1 | Photopolymer formula for producing of holographic media with highly networked matrix polymers | Bayer MaterialScience AG (DE) | 2012-05-09 | — | — | EP | disclosed |