Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826579 | 1.00 | P2RX7 (0.58) | P2RX7ITGB3ITGA2BSYKBCL2 | |
| SCHEMBL1823758 | 0.92 | BCL2 (0.55) | P2RX7ITGB3ITGA2BBCL2CTSL | |
| SCHEMBL1823759 | 0.92 | BCL2 (0.55) | P2RX7ITGB3ITGA2BBCL2CTSL | |
| SCHEMBL2861160 | 0.91 | P2RX7 (0.59) | P2RX7ITGB3ITGA2BBCL2CTSL | |
| SCHEMBL2861161 | 0.91 | P2RX7 (0.59) | P2RX7ITGB3ITGA2BBCL2CTSL | |
| SCHEMBL1824914 | 0.90 | P2RX7 (0.68) | P2RX7ITGB3ITGA2BBCL2 | |
| SCHEMBL1825869 | 0.90 | SYK (0.49) | P2RX7ITGB3ITGA2BSYKCTSL | |
| SCHEMBL1824913 | 0.90 | P2RX7 (0.68) | P2RX7ITGB3ITGA2BBCL2 | |
| SCHEMBL1825917 | 0.89 | ALDH1A1 (0.58) | P2RX7ITGB3ITGA2BCTSLCTSK | |
| SCHEMBL1825915 | 0.89 | ALDH1A1 (0.58) | P2RX7ITGB3ITGA2BCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161254-B1 | Intermediate for preparing a biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |
| US-7714157-B2 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-11 | — | — | US | disclosed |
| EP-2161254-A1 | Intermediate for preparing a biaryl compound | Sumitomo Chemical Company, Limited (JP) | 2010-03-10 | — | — | EP | disclosed |
| US-20070270603-A1 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-11-22 | — | — | US | disclosed |
| US-7271280-B2 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-09-18 | — | — | US | disclosed |
| EP-1481967-A1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | Sumitomo Chemical Company, Limited (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040158093-A1 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158093-A1 | Process for preparing a biaryl compound | CYP1B1, REL, CYP2F1 | P2RX7 3606/4885ITGB3 2686/4885ITGA2B 2709/4885 |
| US-20070270603-A1 | Process for preparing a biaryl compound | CYP4A11, CYP4B1, CYP51A1 | P2RX7 2747/4885ITGB3 4493/4885ITGA2B 4364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.