SCHEMBL18267264

SCHEMBL18267264

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc2c3ccc(-n4c5ccc(C(C)(C)C)cc5c5cc(C(C)(C)C)ccc54)cc3n(-c3cccc4c3ccc3c4ccc4c5ccccc5ccc43)c2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.44
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PGR P06401 1/20 0.36
RORA P35398 1/20 0.36
RORC P51449 1/20 0.36
RORB Q92753 1/20 0.36
HPRT1 P00492 3/20 0.33
KIF11 P52732 2/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
PPARG P37231 3/20 0.33
KCNH2 Q12809 2/20 0.32
MAPK14 Q16539 1/20 0.32
PPARA Q07869 1/20 0.31
NR1I2 O75469 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18267258 1.00 TDP1 (0.44) TDP1CYP1A2CYP2C9CYP2C19PGR
SCHEMBL18267247 0.88 NPC1 (0.33) TDP1PGRRORARORCRORB
SCHEMBL18267259 0.87 CYP1A2 (0.36) TDP1CYP1A2PGRRORARORC
SCHEMBL17774084 0.84 ALDH1A1 (0.34) TDP1CYP1A2PGRRORARORC
SCHEMBL18267253 0.84 ERBB2 (0.42) CYP1A2PGRRORARORCRORB
SCHEMBL17774089 0.84 ATM (0.36) PGRRORARORCRORBKIF11
SCHEMBL15788346 0.84 PPARG (0.38) PGRRORARORCRORBKIF11
SCHEMBL2604398 0.83 KCNH2 (0.37) PGRRORARORCRORBKIF11
SCHEMBL18267265 0.83 KCNH2 (0.32) PGRRORARORCRORBKIF11
SCHEMBL17774125 0.83 PGR (0.43) PGRRORARORCRORBKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361379-B2 Photoelectric conversion element, photosensor, and imaging device FUJIFILM CORPORATION (JP) 2019-07-23 US disclosed
US-20160351830-A1 PHOTOELECTRIC CONVERSION ELEMENT, PHOTOSENSOR, AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2016-12-01 US disclosed
US-20160351830-A1 PHOTOELECTRIC CONVERSION ELEMENT, PHOTOSENSOR, AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2016-12-01 US disclosed