SCHEMBL1826733

SCHEMBL1826733

CCC(C)[SiH](O)C(C)CC

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4516740 0.79
SCHEMBL17024497 0.73 TSHR (0.41) TSHR
SCHEMBL440207 0.69 TSHR (0.38) TSHR
SCHEMBL2018601 0.69
SCHEMBL27697634 0.68
SCHEMBL23700978 0.67 TSHR (0.35) TSHR
SCHEMBL15915908 0.67
SCHEMBL3597293 0.67
SCHEMBL5711199 0.67 TSHR (0.35) TSHR
SCHEMBL2101826 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022129201-A1 PLATELET-LIKE MATTING AGENT FOR POWDER COATING AND POWDER COATINGS ECKART GMBH (DE) 2022-06-23 WO disclosed
EP-2698403-B1 Surface modified pearlescent pigments and their use in powder coatings ECKART GMBH (DE) 2018-01-03 EP disclosed
US-20150244028-A1 NONAQUEOUS SECONDARY CELL, AND FIRE-RETARDANT AGENT AND ADDITIVE FOR NONAQUEOUS SECONDARY CELL WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2015-08-27 US disclosed
CN-102558213-B Silanol-containing triarylamine derivatives SHINETSU CHEMICAL CO 2015-04-15 CN disclosed
EP-2318463-B1 METAL EFFECT PIGMENTS, METHOD FOR THE PRODUCTION AND THE USE THEREOF AND POWDER COATING ECKART GMBH (DE) 2014-10-01 EP disclosed
EP-2457917-B1 Silanol-containing triarylamine derivatives SHINETSU CHEMICAL CO (JP) 2014-06-18 EP disclosed
WO-2014026877-A1 SURFACE-MODIFIED PEARLESCENT PIGMENTS AND THE USE THEREOF IN POWDER COATINGS ECKART GMBH (DE) 2014-02-20 WO disclosed
EP-2698403-A1 Surface modified pearlescent pigments and their use in powder coatings Eckart GmbH (DE) 2014-02-19 EP disclosed
US-8575384-B2 Silanol-containing triarylamine derivatives SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-11-05 US disclosed
US-8304077-B2 Metal effect pigments, method for the production and the use thereof and powder coating ECKART GMBH (DE) 2012-11-06 US disclosed
US-20120149913-A1 SILANOL-CONTAINING TRIARYLAMINE DERIVATIVES SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-06-14 US disclosed
EP-2457917-A1 Silanol-containing triarylamine derivatives Shin-Etsu Chemical Co., Ltd. (JP) 2012-05-30 EP disclosed
US-20110160389-A1 METAL EFFECT PIGMENTS, METHOD FOR THE PRODUCTION AND THE USE THEREOF AND POWDER COATING ECKART GMBH (DE) 2011-06-30 US disclosed
EP-2318463-A1 METAL EFFECT PIGMENTS, METHOD FOR THE PRODUCTION AND THE USE THEREOF AND POWDER COATING Eckart GmbH (DE) 2011-05-11 EP disclosed
WO-2010003660-A1 METAL EFFECT PIGMENTS, METHOD FOR THE PRODUCTION AND THE USE THEREOF AND POWDER COATING ECKART GMBH (DE) 2010-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149913-A1 SILANOL-CONTAINING TRIARYLAMINE DERIVATIVES SIK2, AS3MT, ILK TSHR 2248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.