SCHEMBL182676

SCHEMBL182676

C#Cc1cccc(OC)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CA9 Q16790 3/20 0.49
GRM5 P41594 3/20 0.49
CA12 O43570 2/20 0.49
CA7 P43166 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CYP3A4 P08684 1/20 0.48
CHRM2 P08172 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ENPP2 Q13822 1/20 0.44
FFAR1 O14842 1/20 0.43
EGFR P00533 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29666208 1.00 ACHE (0.50) ACHECA1CA2CA9GRM5
Bromide SCHEMBL28242083 0.98 ACHE (0.48) ACHECA1CA2CA9GRM5
Phenylacetylene SCHEMBL28207925 0.94 CA4 (0.48) ACHECA1CA2CA9GRM5
SCHEMBL3894000 0.92 CA1 (0.46) ACHECA1CA2CA9GRM5
SCHEMBL4523103 0.92 SMN1; SMN2 (0.53) ACHECA1CA2CA9GRM5
SCHEMBL11240283 0.89 HTR2C (0.45) ACHECA1CA2CA9GRM5
SCHEMBL9047946 0.87 LTA4H (0.53) CA1CA2CA9GRM5CA12
Acrolein SCHEMBL27487933 0.86 CHRM2 (0.46) ACHECA1CA2CA9GRM5
SCHEMBL6132140 0.82 GRM5 (0.66) ACHECA1CA2CA9GRM5
SCHEMBL30707880 0.82 GRM5 (0.66) ACHECA1CA2CA9GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059955-A Imidazo pyridone compound, photocatalysis continuous synthesis method and application thereof 南京工业大学 2026-05-19 CN claimed
CN-115872993-B Method for continuously synthesizing piperidone by photoinduction 南京工业大学 2024-12-10 CN claimed
CN-118515716-A NNN-pyridine-quinoline cobalt complex, preparation method and catalytic alkyne hydrosilylation reaction 石河子大学 2024-08-20 CN claimed
CN-118420615-A Method for synthesizing pyridoquinazolinone compound by photo-induced organic catalysis alkyne difunctional cyclization 南京工业大学 2024-08-02 CN claimed
CN-117886829-A Pyridoisocoumarin compound and preparation method and application thereof 河北中烟工业有限责任公司 2024-04-16 CN claimed
CN-113444125-B Phosphoramidite ligand, preparation method thereof and application thereof in asymmetric carbonylation reaction 西北大学 2024-01-26 CN claimed
US-11814462-B2 Functionalized cyclic polymers and methods of preparing same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-14 US claimed
CN-116947915-A Preparation method of vinyl stannane compound catalyzed by aluminum hydrogen 北京理工大学 2023-10-27 CN claimed
CN-116574101-A Method for continuously preparing imidazopyridone compounds by photocatalysis 南京工业大学 2023-08-11 CN claimed
CN-116396313-A Alkenyl borate, and preparation method and application thereof 中山大学 2023-07-07 CN claimed
EP-1551834-B1 SUBSTITUTED QUINAZOLINONE COMPOUNDS NOVARTIS VACCINES & DIAGNOSTIC (US) 2010-08-25 EP claimed
EP-1673349-B1 BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS S BIO PTE LTD (SG) 2010-06-30 EP claimed
EP-1630165-B1 [1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-2-YLUREA DERIVATIVE AND USE THEREOF NIPPON KAYAKU KK (JP) 2010-03-31 EP claimed
EP-1299354-B1 FACTOR VIIA INHIBITORY (THIO)UREA DERIVATIVES, THEIR PREPARATION AND THEIR USE SANOFI AVENTIS DEUTSCHLAND (DE) 2009-07-22 EP claimed
EP-1753512-B1 TETRAHYDROPYRIDOTHIOPHENES NYCOMED GMBH (DE) 2008-07-09 EP claimed
EP-1313713-B1 4-PYRIMIDINAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS ORTHO MCNEIL PHARM INC (US) 2008-06-11 EP claimed
EP-1244617-B1 SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE ORTHO MCNEIL PHARM INC (US) 2005-02-16 EP claimed
EP-0922050-B1 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES ABBOTT LAB (US) 2003-07-30 EP claimed
EP-0690855-B1 BENZOPYRANES AS POTASSIUM CHANNEL OPENERS PFIZER LTD (GB) 1996-12-18 EP claimed
EP-0264908-B1 High sensitivity resists having autodecomposition temperatures greater than about 160 C IBM (US) 1996-03-20 EP claimed