SCHEMBL18267828

SCHEMBL18267828

Cc1ccc(-c2ccc3c(c2)sc2c3ccc3c4ccc(-c5ccc(C)cc5)cc4sc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 13/20 0.41
ESR1 P03372 2/20 0.39
ESR2 Q92731 1/20 0.35
MCL1 Q07820 2/20 0.34
BCL2L1 Q07817 1/20 0.34
CLK1 P49759 1/20 0.34
TNKS O95271 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26324938 0.94 LIMK1 (0.41) LIMK1ESR1ESR2MCL1BCL2L1
SCHEMBL18470294 0.94 LIMK1 (0.41) LIMK1ESR1ESR2MCL1BCL2L1
SCHEMBL17037062 0.94 LIMK1 (0.41) LIMK1ESR1ESR2MCL1BCL2L1
SCHEMBL15599412 0.90 BCL2L1 (0.40) LIMK1ESR1ESR2MCL1BCL2L1
SCHEMBL14680638 0.90 ESR1 (0.41) LIMK1ESR1ESR2MCL1BCL2L1
SCHEMBL18470279 0.87 LIMK1 (0.50) LIMK1TNKSTNKS2
SCHEMBL18267852 0.86 ESR1 (0.40) LIMK1ESR1ESR2MCL1BCL2L1
SCHEMBL15599403 0.86 MCL1 (0.42) LIMK1ESR1ESR2MCL1BCL2L1
SCHEMBL23046392 0.85 TNKS (0.46) LIMK1TNKSTNKS2
SCHEMBL16978726 0.85 LIMK1 (0.37) LIMK1ESR1ESR2TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10008671-B2 Organic thin-film transistor and method for manufacturing same FUJIFILM CORPORATION (JP) 2018-06-26 US disclosed
US-9905768-B2 Semiconductor device and insulating layer-forming composition FUJIFILM CORPORATION (JP) 2018-02-27 US disclosed
US-20170309836-A1 ORGANIC SEMICONDUCTOR LIQUID COMPOSITION, ORGANIC SEMICONDUCTOR ELEMENT, AND METHOD FOR PREPARING ORGANIC SEMICONDUCTOR ELEMENT FUJIFILM CORPORATION (JP) 2017-10-26 US disclosed
US-9799832-B2 Organic thin-film transistor and method for manufacturing same FUJIFILM CORPORATION (JP) 2017-10-24 US disclosed
US-9755160-B2 Thin film transistor FUJIFILM CORPORATION (JP) 2017-09-05 US disclosed
US-20170179415-A1 ORGANIC FIELD-EFFECT TRANSISTOR, METHOD FOR MANUFACTURING ORGANIC SEMICONDUCTOR CRYSTAL, AND ORGANIC SEMICONDUCTOR ELEMENT FUJIFILM CORPORATION (JP) 2017-06-22 US disclosed
US-20170054076-A1 SEMICONDUCTOR DEVICE AND INSULATING LAYER-FORMING COMPOSITION FUJIFILM CORPORATION (JP) 2017-02-23 US disclosed
US-20170005266-A1 SEMICONDUCTOR ELEMENT AND INSULATING LAYER-FORMING COMPOSITION FUJIFILM CORPORATION (JP) 2017-01-05 US disclosed
US-20160372663-A1 ORGANIC THIN-FILM TRANSISTOR AND METHOD FOR MANUFACTURING SAME FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20160351839-A1 ORGANIC THIN-FILM TRANSISTOR FUJIFILM CORPORATION (JP) 2016-12-01 US disclosed
US-20160351824-A1 THIN FILM TRANSISTOR FUJIFILM CORPORATION (JP) 2016-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10008671-B2 Organic thin-film transistor and method for manufacturing same TET1, FTO, TET2 LIMK1 1999/4885ESR1 1616/4885ESR2 3625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.