SCHEMBL15599403

SCHEMBL15599403

Cc1ccc(-c2ccc3c(c2)sc2cc(C)ccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.42
BCL2L1 Q07817 1/20 0.42
ESR1 P03372 3/20 0.40
APP P05067 6/20 0.38
MAPT P10636 6/20 0.38
RAB9A P51151 5/20 0.38
NPC1 O15118 3/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
MAOB P27338 1/20 0.37
LMNA P02545 1/20 0.36
ESR2 Q92731 1/20 0.36
SNCA P37840 2/20 0.36
LIMK1 P53667 1/20 0.35
TNF P01375 1/20 0.35
NOD1 Q9Y239 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15599413 0.96 MCL1 (0.40) MCL1BCL2L1ESR1APPMAPT
SCHEMBL10133862 0.96 BCL2L1 (0.44) MCL1BCL2L1ESR1APPMAPT
SCHEMBL14680638 0.96 ESR1 (0.41) MCL1BCL2L1ESR1MAPTRAB9A
SCHEMBL18267852 0.92 ESR1 (0.40) MCL1BCL2L1ESR1MAPTRAB9A
SCHEMBL25811188 0.90 ESR1 (0.37) MCL1BCL2L1ESR1MAPTRAB9A
SCHEMBL14295769 0.90 LIMK1 (0.44) MCL1BCL2L1MAPTRAB9ANPC1
SCHEMBL15599412 0.88 BCL2L1 (0.40) MCL1BCL2L1ESR1APPMAPT
SCHEMBL812518 0.87 BCL2L1 (0.50) MCL1BCL2L1MAPTRAB9ANPC1
SCHEMBL19335919 0.87 BACE1 (0.35) MCL1BCL2L1ESR1APPMAPT
SCHEMBL9917189 0.86 GPR3 (0.52) ESR1MAPTRAB9ANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11765968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-11765968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-20180212165-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-26 US disclosed
US-20180212165-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-26 US disclosed
US-9761804-B2 Oligomeric organic light emitting diode (OLED) materials containing multiple crosslinking functions LOMOX LIMITED (GB) 2017-09-12 US disclosed
US-9761804-B2 Oligomeric organic light emitting diode (OLED) materials containing multiple crosslinking functions LOMOX LIMITED (GB) 2017-09-12 US disclosed
US-9371484-B2 Organic light emitting diode device and liquid crystal type emitting material for the same LG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
WO-2013167857-A1 OLIGOMERIC ORGANIC LIGHT EMITTING DIODE(OLED)MATERIALS CONTAINING MULTIPLE CROSSLINKING FUNCTIONS LOMOX LIMITED (GB) 2013-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212165-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, TPO, DDT MCL1 2147/4885BCL2L1 1027/4885ESR1 1095/4885
US-11765968-B2 Organic electroluminescent materials and devices TPR, TPO, DDT MCL1 2147/4885BCL2L1 1027/4885ESR1 1095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.