Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18269408 | 1.00 | VDR (0.76) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL18269404 | 0.94 | VDR (0.78) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL16743044 | 0.94 | VDR (0.78) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL22394317 | 0.94 | VDR (0.78) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL22394318 | 0.94 | VDR (0.78) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL18269397 | 0.94 | VDR (0.78) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL22394315 | 0.90 | VDR (0.76) | VDRHDAC6HDAC3HDAC2 | |
| SCHEMBL18269402 | 0.90 | VDR (0.76) | VDR | |
| SCHEMBL18269409 | 0.90 | VDR (0.76) | VDR | |
| SCHEMBL22416531 | 0.87 | VDR (0.62) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160347710-A1 | 1-ALPHA,25-DIHYDROXY-24,24-DIFLUORO-19-NOR-VITAMIN D3 ANALOGS AND THEIR PHARMACEUTICAL USES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347710-A1 | 1-ALPHA,25-DIHYDROXY-24,24-DIFLUORO-19-NOR-VITAMIN D3 ANALOGS AND THEIR PHARMACEUTICAL USES | CYP24A1, VDR, CYP2R1 | VDR 2/4885HDAC6 3565/4885HDAC3 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.