Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | LIPE | Q05469 | 8/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23104808 | 0.88 | USP30 (0.37) | USP30LIPEPRMT5WDR77GABRA1 | |
| SCHEMBL30170561 | 0.87 | USP30 (0.38) | USP30LIPEBACE1BACE2PRMT5 | |
| SCHEMBL24768191 | 0.87 | USP30 (0.38) | USP30LIPEBACE1BACE2PRMT5 | |
| SCHEMBL31152390 | 0.86 | USP30 (0.37) | USP30LIPEPRMT5WDR77FFAR1 | |
| SCHEMBL29363683 | 0.84 | USP30 (0.36) | USP30LIPEBACE1BACE2PRMT5 | |
| SCHEMBL25028824 | 0.84 | USP30 (0.36) | USP30LIPEBACE1BACE2PRMT5 | |
| SCHEMBL13554546 | 0.82 | RET (0.42) | USP30 | |
| SCHEMBL25174282 | 0.81 | BACE1 (0.33) | USP30BACE1BACE2PRMT5WDR77 | |
| SCHEMBL28594656 | 0.81 | HTR6 (0.40) | USP30BACE1BACE2PRMT5WDR77 | |
| SCHEMBL30369811 | 0.81 | BACE1 (0.33) | USP30BACE1BACE2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771048-A | Inhibitors of influenza virus replication and intermediates and uses thereof | 南京药石科技股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| US-20180134730-A1 | IMPROVED PROCESS FOR PREPARING BORYL 7-AZAINDOLE COMPOUNDS | BOROPHARM INC (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180134730-A1 | IMPROVED PROCESS FOR PREPARING BORYL 7-AZAINDOLE COMPOUNDS | BOROPHARM INC (US) | 2018-05-17 | — | — | US | disclosed |
| WO-2016191079-A1 | IMPROVED PROCESS FOR PREPARING BORYL 7-AZAINDOLE COMPOUNDS | BOROPHARM, INC. (US) | 2016-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134730-A1 | IMPROVED PROCESS FOR PREPARING BORYL 7-AZAINDOLE COMPOUNDS | AZI2, BCCIP, ADAR | USP30 2488/4885LIPE 3718/4885BACE1 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.