Methacrylic Acid

Methacrylic Acid

SCHEMBL18270983

C=C(C)C(=O)O.O=C1CCCN1CO

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
TSHR P16473 3/20 0.47
PIK3CD O00329 1/20 0.44
HTT P42858 1/20 0.42
INMT O95050 1/20 0.41
BLM P54132 1/20 0.40
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 2/20 0.38
CHRM2 P08172 1/20 0.38
CHRM5 P08912 1/20 0.38
CYP2D6 P10635 1/20 0.38
CHRM1 P11229 1/20 0.38
ALOX12 P18054 1/20 0.38
NFKB1 P19838 1/20 0.38
CHRM3 P20309 1/20 0.38
APEX1 P27695 1/20 0.38
MAPK1 P28482 1/20 0.38
PMP22 Q01453 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL1817345 0.87 KMT2A (0.48) KMT2ATSHRPIK3CDHTTINMT
Methacrylic Acid SCHEMBL28238503 0.86 INMT (0.53) KMT2ATSHRPIK3CDHTTINMT
SCHEMBL477750 0.83
SCHEMBL1856822 0.77
SCHEMBL27417138 0.76 TSHR (0.47) KMT2ATSHRPIK3CDHTTINMT
SCHEMBL11475147 0.75 KMT2A (0.52) KMT2ATSHRPIK3CDHTTBLM
SCHEMBL11473243 0.75 KMT2A (0.52) KMT2ATSHRPIK3CDHTTBLM
SCHEMBL1358629 0.75 KMT2A (0.52) KMT2ATSHRPIK3CDHTTBLM
Acetic Acid SCHEMBL31290083 0.75 KMT2A (0.53) KMT2ATSHRPIK3CDHTTBLM
Ether SCHEMBL19514154 0.75 PIK3CD (0.47) KMT2ATSHRPIK3CDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9512325-B2 Compositions comprising a reactive monomer and uses thereof ISP INVESTMENTS LLC (US) 2016-12-06 US claimed