Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079668 | 0.90 | CYP3A4 (0.57) | CYP3A4ESR1ESR2ACHEKMT2A | |
| SCHEMBL421378 | 0.89 | BCL9 (0.53) | BCL9CTNNB1ACHEKMT2AKDM4E | |
| SCHEMBL689449 | 0.89 | CYP3A4 (0.63) | CYP3A4ESR1ESR2ACHEKMT2A | |
| SCHEMBL3638907 | 0.89 | CYP3A4 (0.56) | CYP3A4ESR1ESR2KMT2AALDH1A1 | |
| SCHEMBL6139167 | 0.87 | KMT2A (0.56) | CYP3A4KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9538006 | 0.87 | KMT2A (0.56) | CYP3A4KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9716546 | 0.87 | KMT2A (0.56) | CYP3A4KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL32684489 | 0.87 | KMT2A (0.56) | CYP3A4KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL689823 | 0.86 | CYP3A4 (0.59) | CYP3A4ESR1ESR2KMT2AALDH1A1 | |
| SCHEMBL29995062 | 0.86 | CYP3A4 (0.65) | CYP3A4ESR1ESR2ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382699-A | Method for producing polyhydroxyalkanoates using 2-hydroxyisocaproate-CoA transferase | 韩国科学技术院 | 2019-10-25 | — | — | CN | claimed |
| CN-106866402-A | It is a kind of（R）The preparation method of the phenylbutyric acid of 2 hydroxyl 4 | 泰州市产品质量监督检验所 | 2017-06-20 | — | — | CN | claimed |
| CN-106699592-A | Method for preparing lisinopril intermediate | 浙江华海药业股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-105209390-A | Rutile titanium dioxide nanoparticles and ordered acicular aggregates of same | CRISTAL INORGANIC CHEMICALS SWITZERLAND LTD | 2015-12-30 | — | — | CN | claimed |
| CN-102660471-A | Production of chiral alpha-hydroxy acid and its strain by using biological catalysis method | UNIV ZHEJIANG TECHNOLOGY | 2012-09-12 | — | — | CN | claimed |
| CN-102660470-A | Sinorhizobium fredii and its application in producing chiral alpha-hydroxy acid by biologically splitting alpha-hydroxy acid raceme | UNIV ZHEJIANG TECHNOLOGY | 2012-09-12 | — | — | CN | claimed |
| CN-101613279-B | Method for preparing chiral compound of (R)-2-hydroxy-4-phenylbutyrate | HANGZHOU FST PHARMACEUTICAL CO LTD | 2012-06-06 | — | — | CN | claimed |
| CN-101613279-A | The preparation method of chipal compounds (R)-2-hydroxy-4-phenyl ethyl butyrate | HANGZHOU FST PHARMACEUTICALS C | 2009-12-30 | — | — | CN | claimed |
| CN-100415892-C | Process for microbial isomerization of alpha-hydroxycarboxylic acids | BASF AG (DE) | 2008-09-03 | — | — | CN | claimed |
| CN-1809642-A | Process for microbial isomerization of alpha-hydroxycarboxylic acids | BASF AG (DE) | 2006-07-26 | — | — | CN | claimed |
| EP-1383741-A4 | PROCESS FOR THE PREPARATION OF BENAZEPRIL | RANBAXY LAB LTD (IN) | 2006-01-04 | — | — | EP | claimed |
| US-20040152889-A1 | Process for the preparation of benazepril | RANBAXY LABORATORIES LIMITED (IN) | 2004-08-05 | — | — | US | claimed |
| EP-1383741-A2 | PROCESS FOR THE PREPARATION OF BENAZEPRIL | RANBAXY LABORATORIES, LTD. (IN) | 2004-01-28 | — | — | EP | claimed |
| WO-2002076375-A2 | PROCESS FOR THE PREPARATION OF BENAZEPRIL | RANBAXY LABORATORIES LIMITED (IN) | 2002-10-03 | — | — | WO | claimed |
| JP-3200739-A | — | — | None | — | — | JP | disclosed |
| CN-110382699-A | Method for producing polyhydroxyalkanoates using 2-hydroxyisocaproate-CoA transferase | 韩国科学技术院 | 2019-10-25 | — | — | CN | disclosed |
| CN-108004276-A | The structure and circular flow method of a kind of ketone group reduction catalysts system | 山东睿鹰先锋制药有限公司 | 2018-05-08 | — | — | CN | disclosed |
| CN-87101916-A | The preparation method of pharmaceutically active compounds | — | 1988-08-24 | — | — | CN | disclosed |
| EP-0249245-A2 | Antihypertensive dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1987-12-16 | — | — | EP | disclosed |
| US-4257926-A | SIMULTANEOUSLY WITH VULCANIZATION USING A COPOLYCONDENSATE OF A PHENOL, FORMALDEHYDE AND RESORCINOL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152889-A1 | Process for the preparation of benazepril | ACE, ACE2, REN | CYP3A4 27/4885ESR1 3905/4885ESR2 2849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.