Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875785 | 0.93 | CYP3A4 (0.56) | CYP3A4ESR1ESR2POLBKMT2A | |
| SCHEMBL689823 | 0.92 | CYP3A4 (0.59) | CYP3A4ESR1ESR2POLBKMT2A | |
| SCHEMBL29331159 | 0.91 | ALDH1A1 (0.62) | CYP3A4ESR1ESR2POLBKMT2A | |
| SCHEMBL4644534 | 0.91 | CYP3A4 (0.58) | CYP3A4ESR1ESR2POLBKMT2A | |
| SCHEMBL31188847 | 0.91 | CYP3A4 (0.58) | CYP3A4ESR1ESR2POLBKMT2A | |
| SCHEMBL809344 | 0.91 | CYP3A4 (0.58) | CYP3A4ESR1ESR2POLBKMT2A | |
| SCHEMBL688275 | 0.91 | CYP3A4 (0.58) | CYP3A4ESR1ESR2POLBKMT2A | |
| SCHEMBL689630 | 0.91 | CYP3A4 (0.58) | CYP3A4ESR1ESR2POLBKMT2A | |
| SCHEMBL4643939 | 0.89 | CYP3A4 (0.56) | CYP3A4ESR1ESR2POLBKMT2A | |
| SCHEMBL1827149 | 0.89 | CYP3A4 (0.61) | CYP3A4ESR1ESR2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785123-B2 | Direct hierarchical assembly of nanoparticles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-22 | — | — | US | claimed |
| US-9464183-B2 | Rubber composition and pneumatic tire using the same | BRIDGESTONE CORPORATION (JP) | 2016-10-11 | — | — | US | disclosed |
| EP-1724252-B1 | COMPOUND AND COMPOSITION CONTAINING THE SAME | MITSUI CHEMICALS INC (JP) | 2015-10-14 | — | — | EP | disclosed |
| US-8222446-B2 | Method for producing dihydroxybenzene derivative | MITSUI CHEMICALS, INC. (JP) | 2012-07-17 | — | — | US | disclosed |
| EP-1820667-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2012-02-29 | — | — | EP | disclosed |
| CN-101076457-B | Pneumatic tire | BRIDGESTONE CORP | 2011-07-27 | — | — | CN | disclosed |
| EP-1724302-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2011-07-20 | — | — | EP | disclosed |
| EP-1724302-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20110146886-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20110004013-A1 | METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE | MITSUI CHEMICALS, INC. (JP) | 2011-01-06 | — | — | US | disclosed |
| US-7491840-B2 | Compound and composition containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-02-17 | — | — | US | disclosed |
| US-7491840-B2 | Compound and composition containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-02-17 | — | — | US | disclosed |
| US-20080047650-A1 | Rubber Composition And Pneumatic Tire Using The Same | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | disclosed |
| US-20080047650-A1 | Rubber Composition And Pneumatic Tire Using The Same | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | disclosed |
| CN-101076457-A | Pneumatic tire | BRIDGESTONE CORP (JP) | 2007-11-21 | — | — | CN | disclosed |
| EP-1820667-A1 | PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1724252-A1 | COMPOUND AND COMPOSITION CONTAINING THE SAME | Mitsui Chemicals, Inc. (JP) | 2006-11-22 | — | — | EP | disclosed |
| EP-1724302-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2006-11-22 | — | — | EP | disclosed |
| US-20060205971-A1 | Compound and composition containing the same | MITSUI CHEMICALS, INC. (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-0052927-B1 | STRETCHED FILM STRUCTURE OF THE POLY-1,3-PHENYLENE TEREPHTHALATE TYPE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205971-A1 | Compound and composition containing the same | RFC4, RFC5, RFC1 | CYP3A4 2329/4885ESR1 804/4885ESR2 1523/4885 |
| US-20110004013-A1 | METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE | UBE2B, UBE2G2, TUBB2B | CYP3A4 227/4885ESR1 742/4885ESR2 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.