Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16736712 | 0.79 | EPHX1 (0.34) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL18271996 | 0.79 | ALOX15 (0.37) | ALOX15LMNATP53CYP3A4HPGD | |
| SCHEMBL18272103 | 0.79 | ALOX15 (0.53) | ALOX15LMNATP53CYP3A4HPGD | |
| SCHEMBL18272175 | 0.78 | CNR2 (0.33) | CNR2 | |
| SCHEMBL18272071 | 0.77 | ALDH1A1 (0.43) | ALOX15LMNATP53CYP3A4HPGD | |
| SCHEMBL18271902 | 0.76 | ALDH1A1 (0.39) | ALOX15LMNATP53CYP3A4HPGD | |
| SCHEMBL18272170 | 0.75 | SLC6A4 (0.32) | — | |
| SCHEMBL16736668 | 0.75 | KCNK3 (0.34) | KCNH2TMEM97SIGMAR1CNR2 | |
| SCHEMBL18272081 | 0.74 | ALDH1A1 (0.42) | ALOX15LMNATP53CYP3A4HPGD | |
| SCHEMBL18262842 | 0.72 | ALDH1A1 (0.39) | ALOX15LMNATP53CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016190871-A1 | 2,5-DIALKYL-4-H/HALO/ETHER-PHENOL COMPOUNDS | TANSNA THERAPEUTICS, INC. (US) | 2016-12-01 | — | — | WO | disclosed |