SCHEMBL182738

SCHEMBL182738

CN(C)S(=O)(=O)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
APOBEC3G Q9HC16 1/20 0.58
ALDH1A1 P00352 6/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
HTT P42858 1/20 0.58
HSD11B1 P28845 1/20 0.55
MAPT P10636 1/20 0.55
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
HTR6 P50406 1/20 0.50
TNF P01375 1/20 0.50
NOD1 Q9Y239 1/20 0.50
GAA P10253 1/20 0.49
PSIP1 O75475 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19211700 0.97 LMNA (0.64) LMNAAPOBEC3GALDH1A1SMN1; SMN2HTT
Hydrochloric Acid SCHEMBL1017218 0.97 LMNA (0.64) LMNAAPOBEC3GALDH1A1SMN1; SMN2HTT
Water SCHEMBL28154432 0.97 LMNA (0.64) LMNAAPOBEC3GALDH1A1SMN1; SMN2HTT
SCHEMBL11798300 0.95 LMNA (0.62) LMNAAPOBEC3GALDH1A1SMN1; SMN2HTT
SCHEMBL23555189 0.91 LMNA (0.63) LMNAAPOBEC3GALDH1A1SMN1; SMN2HTT
Formic Acid SCHEMBL30498949 0.89 LMNA (0.56) LMNAAPOBEC3GALDH1A1SMN1; SMN2HTT
SCHEMBL4073854 0.86 LMNA (0.63) LMNAALDH1A1SMN1; SMN2HTTMAPT
Hydrochloric Acid SCHEMBL28477859 0.84 LMNA (0.61) LMNAALDH1A1SMN1; SMN2HTTMAPT
SCHEMBL26413509 0.84 APOBEC3G (0.58) LMNAAPOBEC3GALDH1A1HSD11B1KMT2A
SCHEMBL11211293 0.84 APOBEC3G (0.58) LMNAAPOBEC3GALDH1A1HSD11B1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2299 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630529-B2 GCN2 modulator compounds Alesta Therapeutics BV (NL) 2026-05-19 US claimed
US-12515397-B2 Three-dimensional printed part PERIDOT PRINT LLC (US) 2026-01-06 US claimed
US-12486260-B2 Indazolyl-isoxazole derivatives for the treatment of diseases such as cancer MERCK PATENT GMBH (DE) 2025-12-02 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-4200298-B1 1H-PYRROLO[3,2-C]PYRIDINE AND 1H-PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS BRISTOL MYERS SQUIBB CO (US) 2025-05-21 EP claimed
CN-119842341-A Bio-based thumb adhesive for automobiles and preparation method thereof 北京龙苑伟业新材料有限公司 2025-04-18 CN claimed
EP-3697410-B1 BENZIMIDAZOLE DERIVATIVES AND THEIR USES TEIJIN PHARMA LTD (JP) 2024-12-18 EP claimed
EP-3829520-B1 HALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF SYNTARA LTD (AU) 2024-11-27 EP claimed
EP-3792256-B1 PYRIDINE COMPOUNDS AS PI3K-GAMMA INHIBITORS INCYTE CORP (US) 2024-10-23 EP claimed
CN-114728950-B Compounds useful as inhibitors of HELIOS proteins 百时美施贵宝公司 2024-10-18 CN claimed
JP-2002540099-A 2002-11-26 JP claimed
US-20020156064-A1 Compounds and their use as PDE inhibitors SMITHKLINE BEECHAM CORP 2002-10-24 US claimed
US-6428582-B1 Dye mixtures, 1:2 cobalt complex formazan dyes and their use CIBA SPECIALTY CHEMICALS CORPORATION 2002-08-06 US claimed
EP-1163221-A1 SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 2001-12-19 EP claimed
WO-2000056712-A1 SULFONAMIDE DERIVATIVES AS 5-HT7 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 2000-09-28 WO claimed
CN-1262600-A Compositions and method for reducing respiratory depression and attendant side effects of mu opioid compounds DELTA PHARMACEUTICALS INC (US) 2000-08-09 CN claimed
EP-0496119-A1 Flame retardant thermoplastic moulding compounds with higher fluidity BASF Aktiengesellschaft (DE) 1992-07-29 EP claimed
EP-0034432-B1 SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS, CONTAINING THEM YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1984-04-25 EP claimed
US-4228262-A SULFUR COMPOUND ALUMINUM CHLORIDE-TITANIUM CHLORIDE COMPLEX POLYMERIZATION CATALYST IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-10-14 US claimed
US-4161461-A OLEFIN COORDINATION-POLYMERIZATION CATALYST; TRANSITION METAL HALIDE TREATED WITH ORGANIC SULFONE, SULFONAMIDE OR SULFIDE AND GRINDED WITH ALUMINUM AND TITANIUM CHLORIDES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-07-17 US claimed