Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667050 | 0.88 | APOBEC3G (0.52) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E | |
| SCHEMBL182738 | 0.84 | LMNA (0.67) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E | |
| SCHEMBL26413509 | 0.84 | APOBEC3G (0.58) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL19211700 | 0.82 | LMNA (0.64) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E | |
| Water SCHEMBL28154432 | 0.82 | LMNA (0.64) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1017218 | 0.82 | LMNA (0.64) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E | |
| SCHEMBL7760437 | 0.80 | APOBEC3G (0.54) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E | |
| SCHEMBL7764047 | 0.80 | APOBEC3G (0.54) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E | |
| SCHEMBL7022399 | 0.80 | APOBEC3G (0.67) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E | |
| SCHEMBL2372572 | 0.80 | APOBEC3G (0.54) | APOBEC3GHSD11B1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287032-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | MERCK SHARP & DOHME LLC (US) | 2023-09-14 | — | — | US | disclosed |
| WO-2022035917-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | MERCK SHARP & DOHME CORP. (US) | 2022-02-17 | — | — | WO | disclosed |
| EP-3133664-A1 | TRIARYL AMINE THICK LAYER DOPED WITH METAL AMIDES FOR USE AS HOLE INJECTION LAYER FOR AN ORGANIC LIGHT-EMITTING DIODE (OLED) | Novaled GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015031725-A1 | TRANSITION METAL-CATALYZED IMIDATION OF ARENES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-03-05 | — | — | WO | disclosed |
| EP-0017068-B1 | MIXTURES CONTAINING AZODICARBON AMIDE AND ALPHA-AMIDO SULFONES, THEIR PREPARATION AND USE AS A BLOWING AGENTS | BAYER AG (DE) | 1983-01-12 | — | — | EP | disclosed |
| US-4280004-A | ACTIVATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |
| EP-0017068-A1 | Mixtures containing azodicarbon amide and alpha-amido sulfones, their preparation and use as a blowing agents | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230287032-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | NUDT1, NT5C3B, DUT | APOBEC3G 494/4885HSD11B1 2530/4885KMT2A 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.