Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.51 |
| ▸ | TUBB | P07437 | 8/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830074 | 0.85 | TUBB4A (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25855378 | 0.80 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25308227 | 0.75 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10042169 | 0.72 | KMT2A (0.61) | CA1CA2KMT2AMAPTGAA | |
| SCHEMBL3264192 | 0.71 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8424777 | 0.70 | MAPK1 (0.60) | PARP10CA1CA2PARP1PARP2 | |
| SCHEMBL19672751 | 0.69 | KMT2A (0.57) | CA1CA2KMT2AMAPTGAA | |
| SCHEMBL14407750 | 0.69 | KMT2A (0.57) | CA1CA2KMT2AMAPTGAA | |
| SCHEMBL17933653 | 0.69 | L3MBTL1 (0.64) | CA1CA2KMT2AMAPTGAA | |
| Hydrochloric Acid SCHEMBL10554176 | 0.69 | MAPK1 (0.58) | PARP10CA1CA2PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315590-A1 | PYRROLE INHIBITORS OF S-NITROSOGLUTATHIONE REDUCTASE | N30 Pharmaceuticals, LLC (US) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010019909-A1 | PYRROLE INHIBITORS OF S-NITROSOGLUTATHIONE REDUCTASE | N30 PHARMACEUTICALS, LLC (US) | 2010-02-18 | — | — | WO | disclosed |