⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31742499 | 1.00 | — | — | |
| SCHEMBL29859917 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28227586 | 0.97 | — | — | |
| Formaldehyde SCHEMBL28113969 | 0.93 | NAPRT (0.43) | — | |
| Alcohol SCHEMBL29132443 | 0.87 | GBA1 (0.46) | — | |
| Formamide SCHEMBL28526897 | 0.87 | EGFR (0.40) | — | |
| Formic Acid SCHEMBL27823119 | 0.87 | ALDH1A1 (0.44) | — | |
| SCHEMBL4426627 | 0.87 | PIK3CD (0.44) | — | |
| SCHEMBL11160404 | 0.80 | PIK3CD (0.57) | — | |
| Pivalate SCHEMBL28933830 | 0.80 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2254 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390645-A | Dehalogenation method for reducing N heteroaryl halide by using hydrosilane | 浙江科技大学 | 2025-02-07 | — | — | CN | claimed |
| CN-119306558-A | Preparation method of high-performance fuel caged hydrocarbon compound | 中国石油化工股份有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-114890942-B | 3-Bromo-6-chloropyridine-2-carboxylic acid and preparation method thereof | 凯美克(上海)医药科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-117926286-A | Synthesis method of 1-chlorobenzo [4,5] thieno [2,3-c ] pyridine | 中钢天源股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-111471041-B | Synthetic method of oxazolidinone antibacterial drug intermediate | 中国科学院上海药物研究所 | 2022-09-20 | — | — | CN | claimed |
| CN-114890942-A | 3-bromo-6-chloropyridine-2-formic acid and preparation method thereof | 凯美克(上海)医药科技有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-114591250-A | One-step synthesis method of 5-bromo-2-chloropyrimidine | 杭州布朗生物医药科技有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-112500337-B | Synthetic method of 3-bromo-6-chloropyridine formamide | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-112500337-A | Synthetic method of 3-bromo-6-chloropyridine formamide | 苏州康润医药有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-109761959-B | Method for synthesizing Abemaciclib mesylate | 杭州科巢生物科技有限公司 | 2020-09-08 | — | — | CN | claimed |
| CN-109096247-A | A kind of preparation method of the disubstituted pyridine derivate of the bis- aziridinyls of 3H | 上海罕道医药科技有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-106083707-B | A kind of synthetic method of asymmetric heteroaryl thioether | 温州大学 | 2018-10-26 | — | — | CN | claimed |
| CN-106674200-A | Compound containing L-prolinamide fragment, and preparation method and application thereof | 西安交通大学 | 2017-05-17 | — | — | CN | claimed |
| CN-104529881-B | 2-chloro-5-ethyl pyridine preparation method | 苏州施亚生物科技有限公司 | 2017-04-12 | — | — | CN | claimed |
| CN-104529881-A | 2-chloro-5-ethyl pyridine preparation method | SUZHOU SHIYA BIOPHARMACEUTICALS INC | 2015-04-22 | — | — | CN | claimed |
| CN-104447625-A | Benzamide compound or pharmaceutically acceptable salt thereof, and applications of benzamide compound or pharmaceutically acceptable salt thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-03-25 | — | — | CN | claimed |
| CN-104016910-A | Synthetic method of 2-amino-3-chloro-5-bromopyridine | DINGTAO COUNTY YOUBANG CHEMICAL INDUSTRY CO LTD | 2014-09-03 | — | — | CN | claimed |
| CN-101888999-B | Pyridylmethyl-sulfonamide compounds | BASF SE | 2013-12-11 | — | — | CN | claimed |
| CN-103420903-A | Method for synthesizing 5-Bromo-2, 4-dichloropyridine | TIANJIN ANJIN SCIENCE AND TECHNOLOGY DEV CO LTD | 2013-12-04 | — | — | CN | claimed |
| CN-103058921-A | Synthesis method of 3-bromo-6-chloropyridyl-2-formic acid | SUZHOU ZIKANG PHARMACEUTICALS INC | 2013-04-24 | — | — | CN | claimed |