Formaldehyde

Formaldehyde

SCHEMBL28113969

C=O.Clc1ccc(Br)cn1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
EGFR P00533 1/20 0.42
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PIK3CD O00329 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
POLB P06746 1/20 0.38
GRM4 Q14833 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ADRA2A P08913 2/20 0.36
ADRA2B P18089 2/20 0.36
ADRA2C P18825 2/20 0.36
PLAU P00749 1/20 0.36
GBA1 P04062 1/20 0.36
CYP2A6 P11509 1/20 0.36
FPR2 P25090 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182768 0.93
SCHEMBL31742499 0.93
Hydrochloric Acid SCHEMBL28227586 0.90
SCHEMBL29859917 0.90
Formamide SCHEMBL28526897 0.85 EGFR (0.40) NAPRTKDM4EALDH1A1EGFRLMNA
Formic Acid SCHEMBL27823119 0.85 ALDH1A1 (0.44) NAPRTKDM4EALDH1A1EGFRLMNA
SCHEMBL4426627 0.80 PIK3CD (0.44) NAPRTKDM4EALDH1A1EGFRLMNA
Alcohol SCHEMBL29132443 0.80 GBA1 (0.46) NAPRTKDM4EALDH1A1EGFRLMNA
Pivalate SCHEMBL28933830 0.78 ALDH1A1 (0.47) NAPRTKDM4EALDH1A1EGFRLMNA
Tert-Butyl Formate SCHEMBL27842068 0.76 TDP1 (0.43) NAPRTKDM4EALDH1A1EGFRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116621778-A USP inhibitor, preparation method and application thereof 北京华森英诺生物科技有限公司 2023-08-22 CN disclosed
CN-106170489-A New Pyrazolopyrimidine derivative and the purposes as MALT1 inhibitor thereof 诺华股份有限公司 2016-11-30 CN disclosed