Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818499 | 0.90 | AKR1C1 (0.41) | AKR1C1PRMT1ESR1CYP19A1CYP11B2 | |
| SCHEMBL20440724 | 0.87 | AKR1C1 (0.57) | AKR1C1PRMT1MEN1KMT2AALDH1A1 | |
| SCHEMBL28558123 | 0.87 | AKR1C1 (0.52) | AKR1C1PRMT1MEN1KMT2AALDH1A1 | |
| SCHEMBL703633 | 0.87 | AKR1C1 (0.52) | AKR1C1PRMT1MEN1KMT2AALDH1A1 | |
| SCHEMBL10006253 | 0.84 | AKR1C3 (0.50) | AKR1C1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4982106 | 0.84 | AKR1C3 (0.50) | AKR1C1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20440726 | 0.84 | AKR1C1 (0.53) | AKR1C1PRMT1MEN1KMT2AALDH1A1 | |
| SCHEMBL6027509 | 0.84 | AKR1C1 (0.47) | AKR1C1PRMT1ESR1CYP19A1CYP11B2 | |
| SCHEMBL819399 | 0.82 | MEN1 (0.46) | AKR1C1PRMT1ESR1CYP19A1CYP11B2 | |
| SCHEMBL713257 | 0.82 | MEN1 (0.46) | AKR1C1PRMT1ESR1CYP19A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252712-B2 | Polymer dispersant addition to fuel cell electrode inks for improved manufacturability | GM Global Technology Operations LLC (US) | 2012-08-28 | — | — | US | disclosed |
| US-20110117472-A1 | POLYMER DISPERSANT ADDITION TO FUEL CELL ELECTRODE INKS FOR IMPROVED MANUFACTURABILITY | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2011-05-19 | — | — | US | disclosed |
| US-20070015840-A1 | Use of an alkyl ether of hydroxystilbene for the treatment of dry skin | L'OREAL (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1575544-A1 | USE OF AN ALKYL ETHER OF HYDROXYSTILBENE FOR THE TREATMENT OF DRY SKIN | L'OREAL (FR) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004054533-A1 | USE OF AN ALKYL ETHER OF HYDROXYSTILBENE FOR THE TREATMENT OF DRY SKIN | L'OREAL (FR) | 2004-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015840-A1 | Use of an alkyl ether of hydroxystilbene for the treatment of dry skin | CYP8B1, HSD17B11, HSD17B1 | AKR1C1 103/4885PRMT1 4773/4885ESR1 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.