SCHEMBL819399

SCHEMBL819399

COC(=Cc1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
AKR1C1 Q04828 1/20 0.45
TSHR P16473 2/20 0.45
MTNR1A P48039 2/20 0.43
MTNR1B P49286 2/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
HPGD P15428 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
AKR1C3 P42330 1/20 0.42
PRMT1 Q99873 1/20 0.41
ESR1 P03372 1/20 0.41
PLA2G1B P04054 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL713257 1.00 MEN1 (0.46) MEN1KMT2AAKR1C1TSHRMTNR1A
SCHEMBL28483684 0.88 MAPT (0.50) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL6701697 0.88 MEN1 (0.51) MEN1KMT2AMTNR1AMTNR1BALDH1A1
SCHEMBL1827687 0.82 AKR1C1 (0.48) MEN1KMT2AAKR1C1TSHRMTNR1A
SCHEMBL6027509 0.80 AKR1C1 (0.47) MEN1KMT2AAKR1C1TSHRMTNR1A
SCHEMBL2777335 0.79 TSHR (0.50) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL8588497 0.79 TSHR (0.50) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL342989 0.79 TSHR (0.50) MEN1KMT2ATSHRALDH1A1MAPT
SCHEMBL23152622 0.78 AKR1C1 (0.41) MEN1KMT2AAKR1C1TSHRMTNR1A
SCHEMBL11412872 0.78 AKR1C1 (0.41) MEN1KMT2AAKR1C1TSHRMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5530030-A CHLORINATED HYDROXYSTILBENES KIORITZ CORPORATIN (JP) 1996-06-25 US claimed
US-5314693-A Hydroxystilbene compounds KIORITZ CORPORATION (JP) 1994-05-24 US claimed
JP-7118107-A None JP disclosed
JP-5279223-A None JP disclosed
CN-114096250-B Therapies for erythropoiesis protoporphyria (EPP) and X-linked protoporphyria (XLP) 匹兹堡大学 联邦高等教育系统 2025-01-14 CN disclosed
US-11786481-B2 Formulation and process for modulating wound healing BioMendics, LLC (US) 2023-10-17 US disclosed
US-11724998-B2 PXR agonists and uses thereof for gut barrier dysfunction treatment and prevention ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2023-08-15 US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 US disclosed
CN-114262252-A Method for preparing olefin and alkane by catalyzing alkyne with quaternary ammonium salt 云南民族大学 2022-04-01 CN disclosed
CN-114096250-A Novel therapy for erythropoietic protoporphyrinopathy (EPP) and X-linked protoporphyrinopathy (XLP) 匹兹堡大学联邦高等教育系统 2022-02-25 CN disclosed
WO-2021236764-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2021-11-25 WO disclosed
US-5530030-A CHLORINATED HYDROXYSTILBENES KIORITZ CORPORATIN (JP) 1996-06-25 US disclosed
US-5530030-A CHLORINATED HYDROXYSTILBENES KIORITZ CORPORATIN (JP) 1996-06-25 US disclosed
CN-1105973-A Nematicides against pine wood nematodes KIORITZ CORP (JP) 1995-08-02 CN disclosed
JP-H07118107-A NEMATOCIDE AGAINST PINE TREE NEMATODE KIORITZ CORP 1995-05-09 JP disclosed
WO-1994012621-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK (DK) 1994-06-09 WO disclosed
US-5314693-A Hydroxystilbene compounds KIORITZ CORPORATION (JP) 1994-05-24 US disclosed
US-5314693-A Hydroxystilbene compounds KIORITZ CORPORATION (JP) 1994-05-24 US disclosed
JP-H05279223-A AGENT FOR CONTROLLING BURSAPHELENEHUS LIGNICOLUS KIORITZ CORP 1993-10-26 JP disclosed
EP-0024567-A1 2-(4-Aminobutoxy)stilbenes and pharmaceutical compositions comprising these compounds MITSUBISHI KASEI CORPORATION (JP) 1981-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234900-A1 METHODS OF ARENE ALKENYLATION CYBB, CBR3, AHR MEN1 4381/4885KMT2A 2925/4885AKR1C1 675/4885
US-11786481-B2 Formulation and process for modulating wound healing SQSTM1, ATG7, TFEB MEN1 4632/4885KMT2A 3278/4885AKR1C1 1878/4885
US-11724998-B2 PXR agonists and uses thereof for gut barrier dysfunction treatment and prevention NR1H2, NR1H4, NR1H3 MEN1 4829/4885KMT2A 4703/4885AKR1C1 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.