Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16829539 | 0.84 | PTGS2 (0.34) | PTGS2CYP3A4PTGS1TNFRSF1A | |
| SCHEMBL28415789 | 0.84 | PTGS2 (0.35) | PTGS2CYP3A4PTGS1TNFRSF1A | |
| SCHEMBL16829541 | 0.83 | PTGS2 (0.33) | PTGS2CYP3A4PTGS1TNFRSF1A | |
| SCHEMBL18281524 | 0.83 | PTGS2 (0.35) | PTGS2CYP3A4PTGS1TNFRSF1A | |
| SCHEMBL16829542 | 0.82 | PTGS2 (0.34) | PTGS2CYP3A4PTGS1TNFRSF1A | |
| Hydrochloric Acid SCHEMBL28759389 | 0.81 | PDE4A (0.31) | — | |
| SCHEMBL16829384 | 0.81 | PTGS2 (0.33) | PTGS2CYP3A4PTGS1TNFRSF1A | |
| SCHEMBL29287780 | 0.81 | CYP3A4 (0.33) | PTGS2CYP3A4PTGS1TNFRSF1A | |
| SCHEMBL16829540 | 0.80 | CYP3A4 (0.33) | PTGS2CYP3A4PTGS1 | |
| Hydrochloric Acid SCHEMBL16859782 | 0.80 | CYP3A4 (0.32) | PTGS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192961-B2 | Production of heterophasic polymers in gas or slurry phase | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200223950-A1 | Production of Heterophasic Polymers in Gas or Slurry Phase | EXXONMOBIL CHEMICAL PATENTS INC. | 2020-07-16 | — | — | US | disclosed |
| US-10570219-B2 | Production of heterophasic polymers in gas or slurry phase | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180258195-A1 | Production of Heterophasic Polymers in Gas or Slurry Phase | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-09-13 | — | — | US | disclosed |
| US-20180142046-A1 | Catalyst System Comprising Supported Alumoxane and Unsupported Alumoxane Particles | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-05-24 | — | — | US | disclosed |
| US-9809664-B2 | Bimodal propylene polymers and sequential polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-9738779-B2 | Heterophasic copolymers and sequential polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-08-22 | — | — | US | disclosed |
| US-9725537-B2 | High activity catalyst supportation | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160355655-A1 | Bimodal Propylene Polymers and Sequential Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-12-08 | — | — | US | disclosed |
| US-20160355654-A1 | High Activity Catalyst Supportation | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-12-08 | — | — | US | disclosed |
| US-20160355657-A1 | Heterophasic Copolymers and Sequential Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-12-08 | — | — | US | disclosed |