SCHEMBL1828048

SCHEMBL1828048

O=C(c1ccccc1)C1C=CC=CC1(O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 3/20 0.38
HTT P42858 2/20 0.38
ALOX15 P16050 1/20 0.38
HBB P68871 1/20 0.38
EPHX1 P07099 1/20 0.37
CES1 P23141 3/20 0.35
ALDH1A1 P00352 3/20 0.35
CES2 O00748 2/20 0.35
TSHR P16473 2/20 0.35
DAO P14920 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
TRPA1 O75762 1/20 0.34
MAPK1 P28482 1/20 0.34
GSK3B P49841 1/20 0.34
HIF1A Q16665 1/20 0.34
MCL1 Q07820 1/20 0.34
KMT2A Q03164 2/20 0.33
CYP2C19 P33261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1874394 0.84 MAPT (0.38) L3MBTL1NPC1MAPTHTTALDH1A1
SCHEMBL6938598 0.83 L3MBTL1 (0.39) L3MBTL1NPC1MAPTHTTALOX15
SCHEMBL28014454 0.83 NPC1 (0.42) L3MBTL1NPC1MAPTHTTALOX15
2,4-Dihydroxybenzophenone SCHEMBL10615149 0.83 MEN1 (0.61) NPC1MAPTHTTALOX15ALDH1A1
SCHEMBL7851780 0.82 L3MBTL1 (0.41) L3MBTL1NPC1MAPTHTTALOX15
SCHEMBL4621722 0.81 NPC1 (0.40) L3MBTL1NPC1MAPTHTTALOX15
SCHEMBL28413826 0.80 MCL1 (0.41) L3MBTL1NPC1ALDH1A1MCL1KMT2A
SCHEMBL9178594 0.79 L3MBTL1 (0.46) L3MBTL1NPC1MAPTHTTALOX15
SCHEMBL29091452 0.79 NPC1 (0.40) L3MBTL1NPC1MAPTHTTALOX15
SCHEMBL11176223 0.79 AKT1 (0.37) L3MBTL1NPC1MAPTHTTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 EP claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP claimed
JP-1287160-A None JP disclosed
JP-60166305-A None JP disclosed
CN-122056781-A Two-part dental sealant, method of administration with a syringe device, and kit 舒万诺知识产权公司 2026-05-19 CN disclosed
US-12523664-B2 Sensor chip and methods thereof NATIONAL UNIVERSITY OF SINGAPORE (SG) 2026-01-13 US disclosed
WO-2025110168-A1 SILICATE MINERAL AND METHOD FOR PRODUCING SAME 株式会社スーパーナノデザイン 2025-05-30 WO disclosed
US-20240156691-A1 TWO-PHASE COMPOSITION L'OREAL (FR) 2024-05-16 US disclosed
EP-4301316-A1 TWO-PHASE COMPOSITION L'OREAL (FR) 2024-01-10 EP disclosed
US-20230355484-A1 TWO-PHASE COMPOSITION L'OREAL (FR) 2023-11-09 US disclosed
US-20230355483-A1 TWO-PHASE COMPOSITION COMPRISING AT LEAST ONE HYDROCARBON OIL AND AT LEAST ONE ESTER OF CITRIC ACID, WHEREIN THE COMPOSITION IS PREFERABLY A CLEANSING COMPOSITION L'OREAL (FR) 2023-11-09 US disclosed
EP-0174135-A2 Heat-developable color light-sensitive material KONICA CORPORATION (JP) 1986-03-12 EP disclosed
JP-S60166305-A PRODUCTION OF CURED PRODUCT SHOWA DENKO KK 1985-08-29 JP disclosed
EP-0035392-B1 LAMINATED MULTILAYER MATERIAL AND ITS USE AS A PACKAGING OR BUILDING MATERIAL MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-11-23 EP disclosed
US-4397916-A FOOD PACKAGING, CONSTRUCTION MATERIALS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-08-09 US disclosed
EP-0016617-B1 LAMINATED MULTILAYER STRUCTURE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-03-09 EP disclosed
US-4370388-A GRAFTED HIGH DENSITY POLYETHYLENE MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1983-01-25 US disclosed
EP-0035392-A1 Laminated multilayer material and its use as a packaging or building material MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-09-09 EP disclosed
EP-0016617-A1 Laminated multilayer structure MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1980-10-01 EP disclosed
US-4131463-A Electric recording process of images using electron sensitive layer containing trivalent cobalt complex and compound having conjugated π bond system FUJI PHOTO FILM CO., LTD. (JP) 1978-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355484-A1 TWO-PHASE COMPOSITION FFAR2, GK, FFAR1 L3MBTL1 3407/4885NPC1 2241/4885MAPT 3847/4885
US-20230355483-A1 TWO-PHASE COMPOSITION COMPRISING AT LEAST ONE HYDROCARBON OIL AND AT LEAST ONE ESTER OF CITRIC ACID, WHEREIN THE COMPOSITION IS PREFERABLY A CLEANSING COMPOSITION POLG, FFAR2, POLA1 L3MBTL1 3902/4885NPC1 2076/4885MAPT 3491/4885
US-20240156691-A1 TWO-PHASE COMPOSITION FFAR2, DEGS1, FFAR1 L3MBTL1 2605/4885NPC1 3852/4885MAPT 1919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.