SCHEMBL18280699

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12166117	0.93	GAA (0.49)	GAAALDH1A1KDM4ETP53MAPT
	SCHEMBL12166081	0.89	KDM4E (0.52)	GAAALDH1A1KDM4ETP53MAPT
	SCHEMBL18280711	0.86	ALDH1A1 (0.52)	GAAALDH1A1KDM4ETP53MAPT
	SCHEMBL18280712	0.86	MYC (0.53)	ALDH1A1KDM4ETP53MAPTRXFP1
	SCHEMBL31179897	0.78	MYC (0.56)	GAAALDH1A1KDM4ELMNAHSD17B10
	SCHEMBL12166069	0.76	MYC (0.45)	GAAALDH1A1KDM4EMAPTMAP2K1
	SCHEMBL12282047	0.75	NR4A2 (0.48)	GAAALDH1A1KDM4EMAPTLMNA
	SCHEMBL18280705	0.75	DDB1 (0.34)	ALDH1A1KDM4EMAPT
	SCHEMBL12166109	0.75	ELANE (0.50)	ALDH1A1KDM4EMAPTMYCELANE
	SCHEMBL25315400	0.75	DDB1 (0.35)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.