Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15357369 | 1.00 | CTSD (0.47) | CTSDSLC6A2SLC6A4SLC6A3CREBBP | |
| SCHEMBL24569731 | 0.74 | CTSD (0.40) | CTSDSLC6A2SLC6A4SLC6A3CYP2C9 | |
| SCHEMBL24569694 | 0.74 | CTSD (0.40) | CTSDSLC6A2SLC6A4SLC6A3CYP2C9 | |
| SCHEMBL13884141 | 0.72 | ALDH1A1 (0.40) | CTSDCYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL15359750 | 0.72 | SMN1; SMN2 (0.33) | POLBKMT2A | |
| SCHEMBL2350556 | 0.71 | CTSD (0.38) | CTSDSLC6A2SLC6A4SLC6A3CREBBP | |
| SCHEMBL2350562 | 0.71 | CTSD (0.38) | CTSDSLC6A2SLC6A4SLC6A3CREBBP | |
| SCHEMBL31059495 | 0.71 | CYP2C9 (0.46) | CTSDSLC6A2SLC6A4SLC6A3GPBAR1 | |
| SCHEMBL600090 | 0.71 | CYP2C9 (0.46) | CTSDSLC6A2SLC6A4SLC6A3GPBAR1 | |
| SCHEMBL420372 | 0.70 | CYP2C9 (0.45) | CTSDSLC6A2SLC6A4SLC6A3GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160357901-A1 | PEPTIDOMIMETIC COMPOUNDS AND RELATED METHODS | BURGESS KEVIN (US) | 2016-12-08 | — | — | US | disclosed |