Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100416 | 0.84 | PDE3A (0.45) | DNMT1ADRB1LMNAALDH1A1MTOR | |
| SCHEMBL28042109 | 0.81 | DNMT1 (0.50) | DNMT1ADRB1LMNAALDH1A1MTOR | |
| SCHEMBL21211653 | 0.81 | DNMT1 (0.50) | DNMT1ADRB1LMNAALDH1A1MTOR | |
| SCHEMBL5076381 | 0.81 | DNMT1 (0.49) | DNMT1ADRB1LMNAALDH1A1MTOR | |
| SCHEMBL29577808 | 0.80 | DNMT1 (0.48) | DNMT1ADRB1LMNAALDH1A1MTOR | |
| SCHEMBL29577527 | 0.78 | DNMT1 (0.45) | DNMT1ADRB1LMNAALDH1A1MTOR | |
| SCHEMBL18285448 | 0.78 | LMNA (0.48) | DNMT1ADRB1LMNAALDH1A1MTOR | |
| SCHEMBL29578057 | 0.78 | DNMT1 (0.47) | DNMT1ADRB1LMNAALDH1A1MTOR | |
| SCHEMBL29577593 | 0.78 | DNMT1 (0.47) | DNMT1ADRB1LMNAALDH1A1MTOR | |
| SCHEMBL29578007 | 0.77 | DNMT1 (0.46) | DNMT1ADRB1LMNAALDH1A1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016195353-A1 | A USE OF 1'-CYANO-CYTARABINE FOR CANCER TREATMENT | KAINOS MEDICINE, INC. (KR) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016195353-A1 | A USE OF 1'-CYANO-CYTARABINE FOR CANCER TREATMENT | KAINOS MEDICINE, INC. (KR) | 2016-12-08 | — | — | WO | disclosed |