Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2057034 | 0.90 | PDE3A (0.44) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL3510472 | 0.88 | PDE3A (0.43) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL18280905 | 0.84 | DNMT1 (0.48) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL1939478 | 0.82 | PDE3A (0.47) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL3424602 | 0.82 | PDE3A (0.47) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL28379714 | 0.82 | PDE3A (0.47) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL15719855 | 0.82 | PDE3A (0.38) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL7794942 | 0.81 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL51650 | 0.81 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL4971926 | 0.81 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022165386-A1 | LNP AND LMP DELIVERY OF ANTIVIRAL NUCLEOTIDE 5'-PHOSPHATES | VIRBIS LLC (US) | 2022-08-04 | — | — | WO | disclosed |
| EP-2697241-B1 | 1'-SUBSTITUTED PYRIMIDINE N-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-06-12 | — | — | EP | disclosed |