Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MPL | P40238 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18281167 | 0.88 | MEN1 (0.53) | MEN1KMT2ARXFP1ALDH1A1KDM4E | |
| SCHEMBL522958 | 0.84 | MEN1 (0.71) | MEN1KMT2ARXFP1ALDH1A1KDM4E | |
| SCHEMBL9476237 | 0.80 | RXFP1 (0.57) | MEN1KMT2ARXFP1ALDH1A1KDM4E | |
| SCHEMBL3391887 | 0.79 | NR4A1 (0.57) | MEN1KMT2ARXFP1ALDH1A1KDM4E | |
| SCHEMBL31256575 | 0.79 | NR4A1 (0.57) | MEN1KMT2ARXFP1ALDH1A1KDM4E | |
| SCHEMBL6349823 | 0.78 | POLB (0.54) | MEN1KMT2ARXFP1ALDH1A1KDM4E | |
| SCHEMBL31522164 | 0.77 | PTPN1 (0.66) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL344157 | 0.77 | PTPN1 (0.66) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5833643 | 0.76 | CSNK2A1 (0.55) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6917252 | 0.76 | PTPN1 (0.64) | MEN1KMT2AALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11029303-B2 | PAH antibodies and uses thereof | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2021-06-08 | — | — | US | disclosed |
| WO-2016196638-A2 | PAH ANTIBODIES AND USES THEREOF | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11029303-B2 | PAH antibodies and uses thereof | PAH, AHR, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | MEN1 1080/4885KMT2A 726/4885RXFP1 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.