Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334833 | 0.85 | PARP10 (0.64) | PARP10F7PARP1F3HTR2A | |
| SCHEMBL2616889 | 0.78 | PARP10 (0.64) | PARP10PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL1315035 | 0.78 | PARP10 (0.74) | PARP10F7PARP1F3PARP11 | |
| SCHEMBL3369697 | 0.74 | HTT (0.55) | PARP10F7PARP1F3HTR2A | |
| SCHEMBL15282381 | 0.73 | SRD5A1 (0.64) | PARP10F7PARP1F3HTR2A | |
| SCHEMBL154428 | 0.72 | DRD4 (0.64) | PARP10F7PARP1F3HTR2A | |
| SCHEMBL88901 | 0.72 | PARP1 (0.59) | PARP10PARP1HTR2CPNMTPARP11 | |
| Bromide SCHEMBL949153 | 0.71 | DRD4 (0.62) | PARP10F7PARP1F3HTR2A | |
| Hydrochloric Acid SCHEMBL8645796 | 0.71 | F7 (0.55) | PARP10F7PARP1F3HTR2A | |
| Hydrochloric Acid SCHEMBL5767968 | 0.68 | HTR2C (0.96) | PARP10F7PARP1F3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196393-A2 | AUTOPHAGY-INHIBITING COMPOUNDS AND USES THEREOF | PRESAGE BIOSCIENCES, INC. (US) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016196393-A2 | AUTOPHAGY-INHIBITING COMPOUNDS AND USES THEREOF | PRESAGE BIOSCIENCES, INC. (US) | 2016-12-08 | — | — | WO | disclosed |